内支架结合胃镜下局部治疗上消化道癌性狭窄  

Combination Treatment of Gastroesophageal Malignant Stenosis with Stent Implantation and Local Therapy under Gastroscopic Guidance

作　　者：沈琳[1] 杨仁杰[1] 金懋林 杨伯琴 李燕 李洁 杨玉琴 

机构地区：[1]北京大学临床肿瘤学院,北京100036

出　　处：《中国肿瘤》2000年第9期420-422,共3页China Cancer

基　　金：国家"九五"介入医学攻关项目资助课题!(编号 :969070304)

摘　　要：〔目的〕通过置入金属支架并结合胃镜下局部治疗解除失去手术机会的晚期消化道肿瘤患者的管腔狭窄 ,防治支架置入后的管腔再狭窄 ,改善患者生活质量。〔方法〕20例晚期上消化道肿瘤患者接受内支架置入治疗 ,其中15例于支架置入后接受胃镜下局部治疗。〔结果〕所有病例置入支架后进食情况皆有改善 ,且持续1个月以上。15例患者体力状况分级进步1～2个级别。12例患者于支架置入后1～3个月发生管腔再狭窄 ,通过胃镜下局部治疗使狭窄再通 ,症状改善 ,8例患者生存期超过6个月。〔结论〕内支架置入可简便、快速地使消化道再通 ,改善患者进食状况 ,但肿瘤持续生长又可导致管腔再狭窄 ,胃镜下局部治疗可有效控制肿瘤生长 ,防止管腔再阻塞。睵urpose〕To combine mentallic tent with local therapy under gastroscopy to treat malignant stenosis of esophagus and cardia in the un-operable patients and to improve the patient's quality of life 〔Methods〕Twenty patients with malignant stenosis underwent placement of self-expending mentallic stent Fifteen out of 20 patients acceptted local treatment (included PDT or/and microwave therapy or/and intumor injection)under gastroscopy after stent implantation 〔Results〕Stenting immediately relived dysphagia in all patients Upper digestive gut occurred obstruction again after stent placement in 1～3 months in 12 patients After taking microwave therapy or/and intumor injection through gastroscopic guidance,obstruction relieved again There were 15 patients improving 1～2 levels in ECOG Eight patients survived over 6 months after stenting 〔Conclusion〕This combined methods are effective and safe It can quickly relieve patients' symptoms,prevent stenosis again and improve the patient's quality of life

关 键 词：食管肿瘤 胃肿瘤 狭窄 支架 介入疗法 治疗 

分 类 号：R735.05[医药卫生—肿瘤]