老年人大肠癌的临床症状及病理特征分析  

Clinical Symptoms and Pathological Characteristics Analysis of Colon Cancer in Aged Patients

作　　者：方平[1] 林海丽[1] 焦顺昌[1] 

机构地区：[1]解放军总医院肿瘤中心肿瘤内科,北京100853

出　　处：《中华保健医学杂志》2013年第1期37-39,共3页Chinese Journal of Health Care and Medicine

摘　　要：目的总结分析老年人大肠癌的临床病理特征。方法回顾性分析解放军总医院2007年6月～2008年10月,住院手术治疗的170例老年(≥65岁)和79例中青年(<45岁﹚大肠癌患者的临床资料。结果老年大肠癌患者男女比例为1.4:1。临床首发症状,老年组患者以腹胀腹痛﹑排便习惯改变为最初临床症状者分别有30例(17.6%)﹑34例(20.0%),而中青年组分别为27例(34.2%)﹑6例(7.6%),差异有统计学意义。病变部位,老年组直肠癌及右半结肠癌多发,与中青年组相似;但横结肠病变5例(2.9%)明显低于中青年组8例(10.1%),差异有统计学意义。病理组织类型分布,老年组大肠癌病理分型为高中分化腺癌的有81例(47.6%),显著高于中青年组20例(25.3%);而低分化腺癌老年组有47例(27.6%),低于中青年组40例(50.6%),差异具有统计学意义。在分期方面,老年组Ⅳ期48例(28.2%)高于中青年组10例(12.7%),两组存在显著性差异。老年组合并大肠息肉的有22例(12.9%),明显高于中青年组3例(3.8%)。淋巴结转移方面,两组无显著性差异。结论老年人大肠癌男性多见,腹胀、腹痛等伴随症状较中青年少见,病变部位以直肠最为多见,其次是右半结肠和乙状结肠。高中分化的腺癌以及合并息肉的大肠癌明显高于中青年组。老年组所处分期较晚,Ⅳ期明显高于中青年组。Objective To summarize and analyze the clinical symptoms and pathological characteristics of colorectal cancer in aged patients. Methods Retrospectively analyze a total number of 170 cases of colorectal cancer in aged patients（≥65 years old） who received surgery treatment from June 2007 to October 2008 in our hospital. Results Of all the aged patients,the ratio of male to female patients was 1.4 to 1. In aged patients, there were 30 cases （17.6%） of constipation and cramp, and 34 cases （20%） with a change of bowel habit as their initial clinic symptom. However,in the young and middle-aged patients, the distribution of the symptoms was 27 cases （34.2%） and 6 cases （7.6%） respectively. Such difference had statistics significance. Regarding the area of infec- tion, rectal cancer and right hemicolon cancer were prevalent in aged group ,which was similar the middle-aged and young patients. However,infection in transverse colon in aged group amounted to 5 cases （2.9%）,which was significantly lower than the 8 cases （10.1%）found in middle-aged and young patients. Such difference had statistics significance. In terms of pathology distribution,there were 81 （47.6%） cases of well-differentiated adcnocarcinoma in aged group, a number that was significantly higher than the 20 cases found in the young and middle aged group （25.3%）. However,there were 47 cases （27.6%） of poorly differentiated adenocarcinoma in aged group, a number that was lower than the 40 cases （50.6%） of the counterpart group. The statistics showed significant difference. In terms of staging, there were 48 cases （28.2%） of stage IV in the aged group,which is higher than the 10 cases （12.7%） in the other group. Such difference had statistical significance. There were 22 cases （12.9%） of large intestine accompanied by polyps in the aged group, which was significantly higher than the 3 eases（3.8%） in the other group. However,there was no significant difference in terms of spread to nearby lymph nodes

关 键 词：大肠癌 临床病理 老年人 

分 类 号：R735.34[医药卫生—肿瘤]