左房粘液瘤患者的血浆抗凝血酶的变化  

The Changes of Blood Anti thrombin Ⅲ in the Patients with Left Atrial Myxoma

作　　者：潘友民[1] 潘铁成[1] 赵金平[1] 严华[1] 周蔓苓 

机构地区：[1]同济医科大学附属同济医院外科，武汉 430030

出　　处：《同济医科大学学报》2000年第5期437-438,共2页Acta Universitatis Medicinae Tongji

摘　　要：报道了 7例左房粘液瘤 (L AM组 )患者血浆抗凝血酶 (AT )的变化 ,并与 8例瓣膜置换术患者 (瓣膜置换术组 )及 8例健康献血员 (正常对照组 )检测结果进行了对比 ,结果表明 L AM组患者的 AT 含量明显低于瓣膜置换术组及正常对照组 (P<0 .0 5 )。 L AM组中有 4例出现肝素相对耐药现象 ,而瓣膜置换术组无 1例发生 ,差异亦有显著性 (P<0 .0 1)。因此 ,认为对左房粘液瘤患者进行体外循环心内直视手术时应密切观察及监测激活全血凝固时间(ACT)The plasma levels of anti thrombin Ⅲ in 7 patients with left atrial myxoma (group LAM), 8 patients with valvular replacements (group VR) and 8 normal persons (control group) were studied and compared. The results showed that the plasma levels of anti thrombin Ⅲ in LAM patients were significant lower than in the groups of VR and control ( P <0 05). Four cases of 7 LAM patients but none of all VR patients were diagnosed having the relative drug resistant to heparin ( P <0 01). It was suggested that the activated clotting time(ACT) should be carefully monitored and observed to avoid the coagulation during open heart surgery in the patients with LAM.

关 键 词：左房粘液瘤 血浆 抗凝血酶Ⅲ 心内直视手术 

分 类 号：R732.1[医药卫生—肿瘤]