卒中后偏瘫患者手法治疗前后视觉P300的变化  

Effects of manipulation treatment on cognitive function and visual P300 potential of patients after stroke

作　　者：邬守凯[1] 刘玲玉[2] 陈斌[2] 

机构地区：[1]湖北省荆门市第一人民医院创伤骨科,448000 [2]湖北省荆门市第一人民医院神经科

出　　处：《中国康复医学杂志》2013年第3期238-241,共4页Chinese Journal of Rehabilitation Medicine

摘　　要：目的:探讨事件相关电位视觉P300在卒中后偏瘫患者认知功能评估中的价值。方法:将48例卒中后偏瘫患者随机分为两组:治疗组25例,治疗手法为对偏瘫肢体行手法被动运动及定量运动;对照组23例,对患肢仅行良肢位摆放及无规则随意被动运动,两组治疗师选择采用盲法分组,治疗时间均为1.0h/次,每日2次,共1个月。对所有患者治疗前后进行视觉P300检查,使用简易智能量表(MMSE)评估患者的认知功能。结果:治疗组手法康复1个月后,视觉P300的潜伏期明显缩短,波幅明显增高(P<0.01)。治疗后两组患者MMSE分值均增加,但治疗后两组比较无显著性意义(P>0.05)。结论:特定手法治疗可明显改善患者的认知功能,视觉P300这一指标的变化值得进一步跟踪随访。Method：Forty-eight patients were randomly divided into two groups, special manipulation treatment group （25 cases） and control group（23 cases）. Patients in manipulation group were regularly given a passive quantitative movement on affected joints lh/time, 2times/d, for lmonth, while patients in control group were irregularly given a passive movement or ordered to perform an autonomic movement. The visual P300 potential and mini-mental stateexamination （MMSE） assessment were administered pre-treatment and post-treatment （after one month） respectively. Result： ①The latency of visual P300 was severely shortened after the manipulation treatment, and the amplitudeof visual P300 wave was heightened significantly. ②MMSE score increased after manipulation treatment, but the difference was not significant between 2 groups（P〉0.05）.Conclusion： Visual P300 indexes might be useful in measuring cognitive function changes after stroke and the special manipulation treatment could also improve the patient＇s cognitive function.Author＇s address Department of orthopaedics, the First People＇s Hospital, Hubei, 448000

关 键 词：认知障碍 手法 视觉P300 简易精神状况检查 

分 类 号：R743.3[医药卫生—神经病学与精神病学]