^(99m)Tc-Octreotide显像与高频超声在甲状腺实性冷结节定性诊断中的比较  

Comparison on ^(99m)Tc-Octreotide scintigraphy and high-frequency ultrasonography in qualitative diagnosis of thyroid solid and cold nodule

作　　者：陈贵兵[1] 林金海[2] 黄劲雄[1] 何小江[1] 俞浩[1] 许威毅[1] 肖小兰[1] 王璘[1] 

机构地区：[1]厦门大学附属第一医院核医学科,福建厦门361003 [2]厦门大学附属第一医院超声科,福建厦门361003

出　　处：《中国医学影像技术》2013年第3期354-357,共4页Chinese Journal of Medical Imaging Technology

基　　金：2007年厦门市卫生局青年创新科研项目(WQK0703)

摘　　要：目的比较99mTc-Octreotide显像与高频超声在甲状腺实性冷结节定性诊断中的价值。方法对82例高频超声检查为实性结节、甲状腺静态显像呈"冷结节"的患者于超声检查3天内行99mTc-Octreotide显像,并将结果与术后病理结果进行对照。结果 82例患者中,恶性结节31例,良性结节51例。99mTc-Octreotide显像、高频超声及二者联合显像诊断恶性结节的灵敏度、特异度、阳性预测值、阴性预测值和准确率分别为70.97%(22/31)、96.08%(49/51)、91.67%(22/24)、84.48%(49/58)、86.59%(71/82),77.42%(24/31)、84.31%(43/51)、75.00%(24/32)、86.00%(43/50)、81.71%(67/82)及87.10%(27/31)、98.04%(50/51)、96.43%(27/28)、92.59%(50/54)、93.90%(77/82)。结论 99mTc-Octreoti-de显像与高频超声均对定性诊断甲状腺实性"冷结节"具有良好效能,而99mTc-Octreotide显像特异度较高。Objective： To compare the value of 99mTc-Octreotide scintigraphy and high-frequency ultrasonography in qualitative diagnosis of thyroid solid and cold nodule. Methods： Eighty-two patients with solid nodule confirmed by high-frequency ultrasonography and cold nodule confirmed by thyroid scan were enrolled. All patients underwent 99mTc-Octreotide scintigraphy within 3 days, and the results were compared with those of post-surgery pathology. Results： Among 82 patients, there were 31 malignant and 51 benign thyroid nodules. The sensitivity, specificity, positive predicting value, negative predicting value and accuracy rate of 99mTc-Octreotide scintigraphy, high-frequency ultrasonography and combined imaging in detecting thyroid malignant nodules were 70.97% （22/31）, 96.08% （49/51）, 91.67% （22/24）, 84.48% （49/58）, 86.59% （71/82）; 77.42% （24/31）, 84.31% （43/51）, 75.00% （24/32）, 86.00% （43/50）, 81.71% （67/82） and 87.10% （27/31）, 98.04% （50/51）, 96.43% （27/28）, 92.59% （50/54）, 93.90% （77/82）. Conclusion： 99mTc-Octreotide scintigraphy and high-frequency ultrasonography may both offer good efficacy for qualitative diagnosis of thyroid solid and cold nodule, while 99mTc-Octreotide scintigraphy has higher specificity.

关 键 词：甲状腺结节 放射性核素显像 超声检查 

分 类 号：R736.1[医药卫生—肿瘤] R817.4[医药卫生—临床医学]