羟基磷灰石微载体的应用及制备  

Application and Preparation of Hydroxyapatite Micro-carrier

作　　者：冯晓娜[1] 杨宪园[1] 卢婷利[1] 商澎[1] 

机构地区：[1]西北工业大学生命学院,特殊环境生物理学研究所,空间生物实验模拟技术国防重点学科实验室,西安710072

出　　处：《材料导报》2013年第5期87-90,共4页Materials Reports

摘　　要：羟基磷灰石(HA)微载体是由钙磷酸盐组成的具有无毒、耐腐蚀、良好的生物相容性以及骨传导性等优点的微球。综述了HA微载体的制备方法,主要有微乳液形核法、模板-自组装法、高温熔融法、喷雾干燥法等,简要介绍了HA微载体在药物载体、分离纯化、培养细胞等方面的应用,展望了HA微载体今后的发展。Hydroxyapatite micro-carrier is a kind of microspheres, with advantages of non-toxic, corrosion re- sistance, good biocompatibility and bone conductivity. The preparation method of hydroxyapatite micro-carrier are re- viewed,including microemulsion method, template-assembly method, high temperature melting method, spray-drying method. Hydroxyapatite micro-carrier is widely used in drug control and release, substrate of separation, microcar- riers of cell culture. The future of hvdroxvaDatite micro-carrier is DrosDected.

关 键 词：羟基磷灰石 微载体 生物相容性 喷雾干燥 

分 类 号：TQ174[化学工程—陶瓷工业]