基于现代文献的动脉粥样硬化中医病机研究  

Distribution of TCM syndrome factors of atherosclerosis based on modern literature

作　　者：王椿野[1,2] 赵振武[1,2] 李新龙[1,2] 李麒豫[1,2] 董洪坦[1,2] 郭蓉娟[1] 

机构地区：[1]北京中医药大学东方医院脑病二科,100029 [2]北京中医药大学

出　　处：《环球中医药》2013年第2期92-95,共4页Global Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)(2012CB518406);首都医学科技发展基金项目(SF-2009-II-07);北京中医药大学创新团队项目(2011-CXTD-23)

摘　　要：目的通过对现代文献的分析研究,总结动脉粥样硬化中医证候要素的特征,进而分析其病机特点。方法在中国学术期刊全文数据库(CNKI)、万方数据资源系统(WANFANGDA-TA)上检索近5年与动脉粥样硬化相关的文献,对证候要素进行频数、频率的统计分析。结果符合要求的文献共72篇,涉及证候要素9种。其中证候分型调研文献13篇,涉及总病例数3606例,证候要素由高至低为血瘀(74.13%)、痰浊(62.92%)、热邪(43.01%)、阴虚(29.37%)、血虚(25.01%)、气滞(23.29%)、气虚(19.72%)、毒邪(12.76%)、阳虚(9.87%);医家论点文献为59篇,涉及医家59位,证候要素由高至低为血瘀(93.22%)、痰浊(74.58%)、气虚(54.24%)、阴虚(30.51%)、毒邪(28.81%)、热邪(23.73%)、阳虚(8.47%)、气滞(3.4%)、血虚(1.7%)。结论痰瘀互结是动脉粥样硬化的主要病理机制。Objective Objective Through the study of modern literature, summary distribution characteristics of TCM syndrome factors of atherosclerosis and analyze its pathogenesis characteristics. Methods Two Chinese biomedical databases （ CNKI and WANFANG） were selected. The modern documents about atherosclerosis from 2008 to 2012 were retrieved and a database was established. Frequency of Syndrome factors was counted and analyzed. Results There were 72 qualified documents colleted which involved nine kinds of syndrome factors. According to 13 Clinical research literatures among them, the total number of cases was 3606 and frequency of Blood stasis was the highest （74.13%） followed by phlegm syndrome （62.92%）, heat syndrome （ 43.01% ）, yin deficienct syndrome （ 29.37% ）, blood deficienct syndrome（25.01% ）, the stagnation of qi （23.29%）, qi deficienct syndrome （ 19.72% ）, toxin syndrome （12.76%） and yang deficient syndrome（9.87% ）. According to 59 literatures discussed by doctors, frequency of Blood stasis was the highest（93.22% ） followed by phlegm syndrome （74.58%）, qi deficienct syndrome （ 54.24% ） , yin deficienct syndrome （ 30.51% ） , toxin syndrome （ 28.81% ）, heat syndrome （23.73%）, yang deficient syndrome（8.47% ）, the stagnation of qi（3.4% ） and blood deficienct syndrome（25.01% ）. Conclusion Phlegm and blood stasis is the main pathogenesis of atherosclerosis.

关 键 词：动脉粥样硬化 中医 病机 证候要素 文献研究 

分 类 号：R228[医药卫生—中医基础理论]