生长抑素治疗颈淋巴结清扫术后难治性乳糜漏的疗效  

Outcomes of treating refractory chylous leakage after neck dissection with somatostatin

作　　者：刘方舟[1] 张园[1] 虞同华[1] 

机构地区：[1]江苏省肿瘤医院头颈外科,210009

出　　处：《江苏医药》2013年第5期531-533,共3页Jiangsu Medical Journal

摘　　要：目的观察生长抑素治疗颈淋巴结清扫术后难治性乳糜漏的临床疗效。方法颈淋巴结清扫术后难治性乳糜漏16例分为两组:B组,10例,采用局部加压、负压引流和低脂饮食;A组,6例,加用生长抑素6mg,溶于500ml生理盐水中静脉泵维持24h治疗,比较两组疗效。结果 A组乳糜漏闭合率为100%,明显高于B组的50%(P<0.05)。A组住院时间为(11.2±4.4)d,明显短于B组的(16.7±4.8)d(P<0.05)。结论生长抑素可有效提高颈淋巴结清扫术后难治性乳糜漏的闭合率,缩短住院时间。Objective To observe the clinical efficacy of treating refractory chylous leakage after neck dissection with somatostatin. Methods Sixteen patients with refractory chylous leakage after neck dissection were divided into two groups. The patients in group B were treated with conventional treatment of local compression, drainage with negative pressure and low fat diet. The patients in group A were treated with additional somatostatin 6 mg in 500 ml normal saline, which was infused intravenously for 24 hours. The clinical efficacy was compared between two groups. Results The close rate of cyhle fistula of group A was 100%, which was higher than 50% of group B （P〈0. 05）. The hospital stay of group A was （11.2±4. 4） d,which was shorter than （16.7±4. 8） d of group B（P〈0. 05）. Conclusion Somatostatin is effective in elevating the close rate of cyhle fistula and shortening the hospital stay in the patients with refractory chylous effusion after the operation of lymphonodi cervicales.

关 键 词：生长抑素 乳糜漏 颈部淋巴结清扫术 

分 类 号：R739[医药卫生—肿瘤]