卵巢原发性类癌6例临床病理分析  

Primary carcinoid of the ovary:a clnicopathologic analysis of 6 caces

作　　者：王春兰 耿振宏[2] 胡营营[3] 王琳琳 李青 李新功 

机构地区：[1]垦利县人民医院病理科,山东东营257500 [2]胜利石油管理局胜利医院病理科,山东东营257055 [3]胜利油田中心医院病理科,山东东营257001 [4]东营市人民医院病理科,山东东营257091

出　　处：《诊断病理学杂志》2013年第3期157-160,共4页Chinese Journal of Diagnostic Pathology

摘　　要：目的对卵巢原发性类癌进行临床病理观察。方法复习6例原发性卵巢类癌临床病理资料,对部分病例补做免疫组化,并观察分析肿瘤的病理组织学特点。结果患者年龄21～59岁,平均50.7岁;4例为下腹部隐痛,2例为查体发现盆腔肿块。肿瘤位于左侧卵巢4例,右侧2例。肿瘤长径3～6.8 cm,界限清楚,多为实性;瘤细胞呈巢状及小梁状排列。所有病例免疫组化神经内分泌标记CgA和Syn均(+),α-inhabin、CD99、ER、PR、CK7、AFP和TTF-1(-);其中1例黏液型CK20(+),1例巢状型和1例黏液型CDX-2弱(+)。随访13～131个月,5例健在,1例失访。结论原发性卵巢类癌较少见,具有与胃肠道类癌相似的组织学形态,预后良好。Objective To study the clinical and pathologic features of primary carcinoid of the ovary. Methods Six cases of primary carcinoid of the ovary, from four hospital and 2001-2010, were analysed about clincal data, histopathology try. Results The age range of six patients was 21-58 years （Mean 50. 7 years）. Four patients presented with dull pain on hypogastrium, two with pelvic mass finded for a health check-up. The left ovary was involved initially in four patients, and the right in two. The major axis of the tumour range were 3 em - 6. 8 cm. These tumors were well circumscribed and solid. The paraffin-embedded tissues of all cases showed immunoreactivity for CgA and Syn, and ot-inhabin, and CD99,ER, PR, CK7, AFP and rlTF-1 were negative in all cases. One case of mucinous type was CK20- positive, one ease of insular type and one case of mucinous type showed weak cytoplasmic positivity for CDX-2. Follow-up of 13 to 131 months showed that five patients were alive and one case was lost contact. Conclusion Primary carcinoid of the ovary is a rare tumour and histologically similar to gastrointestinal carcinoid. Prognosis of primary carcinoid of the ovary is generally favorable.

关 键 词：卵巢肿瘤 畸胎瘤 类癌 病理学 

分 类 号：R737.31[医药卫生—肿瘤]