新疆伊犁地区不同民族帕金森病患病率及相关因素分析  

Analysis of prevalence and related factors in different national Pakinson′s disease in Yili of Xinjiang area

作　　者：张建龙[1] 王玉玲[1] 姚亚妮[1] 杨新玲[1] 

机构地区：[1]新疆医科大学第一附属医院神经医学中心,乌鲁木齐830054

出　　处：《新疆医科大学学报》2013年第3期273-277,共5页Journal of Xinjiang Medical University

基　　金：国家自然科学基金(81160143);新疆维吾尔自治区科技支疆项目(201191162);乌鲁木齐市科学技术计划项目基金(Y09131005);乌鲁木齐市新市区科学技术计划项目基金(Y2011026)

摘　　要：目的探讨新疆伊犁地区常住居民中哈萨克族(哈族)、汉族、维吾尔族(维族)、回族帕金森病(Parkin-son′s disease,PD)的患病率及相关因素。方法应用分层、分段、整群、随机的抽样原则,在新疆伊犁地区随机抽取新源县10个乡镇年龄≥35岁符合调查要求且资料完整者5 113人进行流行病学问卷调查,其中哈萨克族(哈族)2 318人,汉族1 474人,维吾尔族(维族)968人,回族245人,其他民族46人。35～44岁108人,45～54岁2269人,55～64岁1 400人,65～74岁919人,75～84岁308人,≥85岁47人。结果5 113人中PD患者62例,总患病率为1.2%。其中哈族、汉族、维族、回族PD患病率分别为1.2%、1.1%、1.5%和1.2%,35～44岁、45～54岁、55～64岁、65～74岁、75～84岁、≥85岁人群的患病率分别为0%、0.7%、1.3%、2.0%、2.9%、2.1%。单因素分析结果表明:体力劳动(农民)、农药接触史、PD家族史、食用烧烤可增加PD的发病风险、饮酒、饮茶及食用坚果可减少PD的发病风险。多因素条件性Logistic回归分析结果表明:农药接触史是PD的危险因素,吸烟是PD的保护因素。结论农民、体力劳动、农药接触史、PD家族史、食用烧烤可能是危险因素,饮酒、饮茶、食用坚果、吸烟可能是保护因素。Objective To explore the prevalence rate and related factors of Hui Pakinsonrs disease（PD） in Kazak, Han, Uygur residents of Yili in Xinjiang, area. Methods Application of hierarchical sampling principle, segmentation, cluster were used in the Xinjiang region of Yili Xinyuan county in 10 townships. 35 Years of age or older with survey requirements and complete data on 5 113 people were randomly select ed from for epidemiological survey. cases, respectively. There were 46 Nationalities of Kazak, Han, Uygur other nations. The age distributions： Hui were 2 318, 1 474, 968, 245 35--44 years old, 108 people, 45 --54 years old, 2 269 people, 55--64 years old, 1 400 people, 65--74 years old, 919 people, 75--84 years old 308, 85 years old, 47 people. Results There were 62 cases of PD in 5 113 patients, the total preva lence rate was 1.2%. Among the Han, Uygur, Kazak, Hui nationalities, the prevalence rate of PD was 1.2%, 1.1%, 1.5% and 1.2%, respectively. Among the people with 35--44 years, 45--54 years, 55-- 64 years, 65--74 years, 75--84 years of age, the population aged 85 years and above the prevalence rates were 0.0%, 0.7%, 1.3%, 2.0%, 2.9%, 2.1%. The results of single factors analysis showed that the farmer, manual labor, pesticide exposure history, family history of PD, eat barbecue can increase PD risk, drinking, drinking tea and edible nuts might reduce PD risk. Multivariate conditional logistic regression analysis the results showed that the protective factor of PD. Conclusion pest The icide exposure history was a risk factors for PD, smoking were farmer, manual labor, pesticide exposure history, family history of PD, eat barbecue are risk factors, drinking, tea drinking, edible nuts and smoking was the protective factors.

关 键 词：帕金森病 患病率 保护因素 危险因素 

分 类 号：R742.5[医药卫生—神经病学与精神病学]