重症肌无力临床疗效分析(附68例报告)  

Clinical features and efficiency of treatment for myathenia gravis patients (A report of 68 cases)

作　　者：于逢春[1] 耿稚萍[1] 余华锋[1] 张晓君[1] 

机构地区：[1]首都医科大学附属北京同仁医院神经内科,邮政编码100730

出　　处：《北京医学》2000年第5期270-273,共4页Beijing Medical Journal

摘　　要：目的　研究不同年龄组重症肌无力 ( MG)患者的临床特点及疗效。方法　将 68例MG患者按不同年龄分为少儿期 MG、青年期 MG和中老年期 MG三组 ,对其临床资料进行统计学分析比较。结果　少儿组以胸腺增生为主 ( 10 / 11例 ) ,较其余两组有显著性差异 ( P<0 .0 1)且手术治疗效果好 ,无合并症。青年组胸脉增生 ( 14/ 2 8)较中老年组多 ( P<0 .0 1) ,合并其他免疫性疾病多见。中老年组胸腺增生 7例 ,胸腺瘤 8例 ( 4例恶性 )较青年组多 ( P<0 .0 1)且药物及手术治疗预后差。结论　不同年龄组 MG患者的临床分型及病理类型不同 。Objective To explore the clinical features and efficiency of treatment for myathenia gravis (MG) patients in different age groups.Methods Sixty eight MG patients were divided into three groups by patients' age,which were children group (≤14 years),young group (aged 15～39 years) and middle and old aged group (aged more than 40 years).The clinical features were compared and analyzed among the 3 groups.Results The children group had more thymus hyperplasia(10/11) than the other two groups ( P <0 01).Thymus hyperplasia in the young group (14/28) was also more than in the middle and old aged group ( P <0 01).The young group patients had more accompanied immunological diseases.There were more thymus tumors in the middle and old aged group (8/15) than in the young group ( P <0 01) and the surgical or medical treatment effect was poor.Conclusions There are different clinical and pathological teasures in different age groups of MG patients,and also different efficiency treatment and prognosis.

关 键 词：重症肌无力 病理 治疗 临床特点疗效 

分 类 号：R746[医药卫生—神经病学与精神病学]