肝脏CT血流灌注联合血清标志物诊断早期肝硬化的意义  

Hepatic CT Perfusion Combined with Serum Markers for Diagnosis of Early Cirrhosis Significance

作　　者：刘元豪 

机构地区：[1]荆门市第一人民医院感染科,荆门448000

出　　处：《中国医药导刊》2013年第2期229-229,231,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨肝脏CT血流灌注联合血清标志物检测在早期肝硬化诊断中的临床应用价值。方法:回顾性分析120例早期肝硬化患者的生化及影像学资料,并与100例正常体检者进行比较。结果:观察组的BF、PS和HAF指标高于对照组,BV及MTT指标低于对照组(P<0.05);观察组的血清Ⅲ型前胶原肽、CIV、HA、LN值均显著高于对照组(P<0.05)。结论:采用肝脏CT血流灌注血流动力学指标测量联合血清标志物检测,能对早期肝硬化做出无创性诊断。Objective：Hepatic CT perfusion combined with serum markers in the early diagnosis of liver cirrhosis clinical application value.Methods：Retrospective analysis of 120 cases of early liver cirrhosis patients with biochemical and imaging data,and in 100 normal subjects.Results：The observation group BF,PS and HAF index higher than that of the control group,BV and MTT index lower than that of control group（P0.05）;observation of serum procollagen peptide,CIV,HA,LN values were significantly higher than those in control group（P0.05）.Conclusion：The hepatic CT perfusion hemodynamic indices measurement of joint detection of serum markers for early liver cirrhosis,can make noninvasive diagnosis.

关 键 词：肝硬化 灌注成像 CT 血清标志物 

分 类 号：R575.2[医药卫生—消化系统]