启明丸治疗年龄相关性黄斑变性的临床疗效及对血浆Hcy水平的影响  

Clinical efficacy and plasma Hcy levels of Qiming pills on patients with senile macular degeneration

作　　者：卓耀[1] 彭廷云[1] 

机构地区：[1]湖南中医药大学第一附属医院,长沙410007

出　　处：《中国中医眼科杂志》2013年第1期36-38,共3页China Journal of Chinese Ophthalmology

摘　　要：目的观察启明丸治疗年龄相关性黄斑变性(AMD)肝肾阴虚型患者的临床疗效及对血浆同型半胱氨酸(Hcy)水平的影响。方法将肝肾阴虚型AMD患者62例98眼随机分为治疗组(32例52眼)和对照组(30例46眼),其中治疗组予常规治疗联合启明丸;对照组予常规治疗。30天后比较两组患者的临床疗效和血浆Hcy水平、视觉诱发电位(P-VEP)。结果治疗组患者有效率为78.84%,对照组患者有效率为56.52%,二者比较,差异有统计学意义(P<0.05),治疗组优于对照组。两组患者血浆Hcy水平以及视觉诱发电位比较,差异均有统计学意义(P<0.01)。结论启明丸可以明显改善AMD肝肾阴虚型患者的症状。OBJCTIVE To observe the efficacy and plasma homocysteine（Hcy） levels of Qiming pills on patients with yin deficiency of liver and kidney of age-related macular degeneration（AMD）.METHODS Sixty-two patients with AMD（98 eyes）were randomly divided into treatment group（32 patients and 52 eyes） and control group（30 patients and 46 eyes）,in which treatment group was combined conventional treatment with Qiming pills,while for control group was with conventional treatment only.Thirty days later,the clinical efficacy and plasma Hcy levels,visual evoked potential（P-VEP） and Amsler table of the two groups were compared.RESULTS The effective rate for treatment group was 78.84% while the control group was 56.52%.The difference between the two groups was significant（P〈0.05）.The plasma Hcy levels,P-VEP and Amsler table between the two groups of patients were significantly different（P〈0.05）.CONCLUSION The effect of Qiming pills for AMD patients with yin deficiency of liver and kidney was positive,which could improve symptoms and related indicators significantly.

关 键 词：启明丸 黄斑变性 血浆同型半胱氨酸(Hcy) 视觉诱发电位 

分 类 号：R774.5[医药卫生—眼科]