局部晚期直肠癌术前同步放化疗的疗效观察  

Curative effect of concomitant chemoradiotherapy for locally advanced rectal cancer

作　　者：叶兴发[1] 董柱清[1] 吴传高[1] 

机构地区：[1]福建医科大学附属闽东医院放疗科,福建宁德355000

出　　处：《中国医药科学》2013年第5期56-57,共2页China Medicine And Pharmacy

摘　　要：目的观察局部晚期直肠癌行术前放疗联合口服希罗达同步化疗的疗效观察。方法 45例局部晚期直肠癌随机分成术前同步放化疗组(观察组)和术前单纯放疗组(对照组),并将两组治疗效果进行比较。结果术前同步放化疗组(观察组)CR+PR有效率为80.0%,19例(76.0%)患者接受了手术治疗,1例拒绝手术;术前单纯放疗组(对照组)CR+PR有效率为50.0%,9例(45.0%)患者接受了手术治疗,1例拒绝手术;两组比较差异有统计学意义(P<0.05)。结论术前放疗同步联合口服希罗达治疗局部晚期直肠癌效果较好。Objective To observe the curative effect of preoperative radiotherapy combining Xeloda which was an oral chemotherapy drug for the locally advanced rectal cancer. Methods 45 patients with locally advanced rectal cancer were randomly divided into chemoradiation group （observation group） and preoperative simple radiation therapy group（control group）,and compared the treatment effect of the two groups. Results The CR ＋ PR effectiveness of preoperative chemoradiation group（observation group）was 80.0%,19 patients （76.0%） patients who undergo surgery,and 1 case refused to surgery. CR ＋ PR effective rate of preoperative simple radiation therapy group （control group） was 50.0%,9 cases （45.0%） patients who undergo surgery,and 1 case refused to surgery,there were significant differences between the two groups（P 〈 0.05）. Conclusion The preoperative radiotherapy combining xeloda can get a good curative effect for locally advanced rectal cancer.

关 键 词：局部晚期直肠癌 同步放化疗 希罗达 

分 类 号：R735.36[医药卫生—肿瘤]