脑梗死患者IMT与AIP的关系  

The relationship between atherogenic index of plasma and carotid intima-media thickness in patients with cerebral infarction

作　　者：江飞飞 丁美萍[1] 俎德玲[3] 诸葛毅[4] 

机构地区：[1]浙江大学附属第二医院神经内科,浙江杭州310009 [2]浙江省衢州市人民医院神经内科,浙江衢州324000 [3]浙江省衢州市人民医院心血管内科,浙江衢州324000 [4]浙江衢州职业技术学院医学院,浙江衢州324000

出　　处：《中风与神经疾病杂志》2013年第3期238-239,共2页Journal of Apoplexy and Nervous Diseases

摘　　要：目的探讨血浆致动脉硬化指数(AIP)及颈内动脉内中膜厚度(IMT)与脑梗死发生的关系。方法经头部CT和(或)MRI检查确诊的120例脑梗死患者(脑梗死组)及60例健康体检者(对照组),采用多普勒超声检测IMT,并测定甘油三酯(TG)、高密度脂蛋白(HDL-C),计算出AIP,进行统计学处理。结果 (1)与对照组相比,脑梗死组患者呈现高TG、低HDL-C及AIP值明显升高;(2)与对照组相比,脑梗死组患者颈内动脉IMT明显高于对照组(P<0.01);(3)颈内动脉内中膜厚度与AIP呈正相关。结论血浆致动脉硬化指数、颈内动脉IMT与脑梗死的发生密切相关。Objective To investigate the relationship between atherogenic index of plasma and carotid intima-media thick- ness in patients with cerebral infarction. Methods Intima-media thickness（IMT）were examined with color Doppler ultrasound in 120 patients with cerebral infarction confirmed by cranial CT and（or）MRIIand 50 subjects as controls ;the level of triglyceride （TG）, high density lipo-protein cholesterol（HDL-C） and atherogenic index of plasma（AlP）were determined in 120 patients with cerebral infarction confirmed by cranial CT and （or）MR] and 60 subjects as controls. Results The levels of TG and AlP in- creased significantly in patients with cerebral infarction ;tThe levels of HDL-C decreased significantly in patients with cerebral in- farction;tThe IMT difference between cerebral infarction patients and controls were significantly different（P 〈 0. 01 ）. IMT was correlated with AlP（r = 0. 266,P 〈0.01 ）. Conclusion The development of cerebral infarction is closely correlated with the ca- rotid IMT and AIP.

关 键 词：脑梗死 血浆致动脉硬化指数 颈内动脉内中膜厚度 

分 类 号：R743.3[医药卫生—神经病学与精神病学]