黄芪提取液对小白鼠离体子宫收缩活动的影响  

Astragalus Extract to the Little White Rat in Vitro The Influence of Uterine Contraction Activities

作　　者：丁小莉[1] 曾祥氨[1] 杨彩虹[1] 黄运[1] 吴君相[1] 赵善民[2] 黄彦峰[2] 

机构地区：[1]右江民族医学院,临床医学本科百色533000 [2]右江民族医学院生理教研室,百色533000

出　　处：《航空航天医学杂志》2013年第3期281-283,共3页Journal of Aerospace medicine

基　　金：右江民族医学院普高学生科研项目立项(右医科字〔2012〕24号)

摘　　要：目的:探讨黄芪提取液对小白鼠离体子宫收缩活动的影响。方法:以生理盐水组作对照,采用离体器官灌流的方法,分别滴加生理盐水,不同浓度黄芪提取液(1 g.ml-1、2 g.ml-1、3 g.ml-1)各0.2 ml,2单位缩宫素,观察小白鼠离体子宫收缩活动曲线下面积的变化。结果:滴加生理盐水后对离体子宫收缩活动曲线下面积的影响不显著,而滴加黄芪提取液(1 g.ml-1,2 g.ml-1、3 g.ml-1)后,离体子宫收缩曲线下面积增加明显(P﹤0.05),缩宫素组子宫收缩曲线下面积增加更显著(P﹤0.01),子宫收缩曲线下面积增加均具有统计学意义。结论:黄芪提取液有增强离体子宫收缩活动的功效。Objective：To investigate astragalus extract to the little white rat in vitro the influence of uterine contraction activities. Methods：To physiological saline as a control group, the in vitro organ perfusion method, respectively drop and physiological saline, different concentration astragalus extract （ 1 g·ml^-1 , 2 g·ml^-1 , 3 g·ml^-1 ） , oxytocin each 0. 2 ml, observation of mice in vitro uterine contraction activities of the area under the concentration - time curve changes. Results ： Drop and physiological saline after the in vitro uterine contraction activities of the influence of the area under the concentration - time curve was not significant, but that drop and astragalus extract （ 1 g·ml^-1, 2 g·ml^-1, 3g·ml^-1 ） , in vitro uterine contraction area under curve significantly increased （ P 〈 0. 05 ） , oxytocin group of uterine contraction curve area increase more significant （ P 〈 0. 01 ）, uterine contraction curve area increase which will have a statistics meaning. Conclusions：Astragalus extract have enhanced in vitro uterine contraction activities of the efficacy.

关 键 词：黄芪 提取液 小白鼠 离体子宫 

分 类 号：R-332[医药卫生]