TACE联合PMCT治疗肝癌的临床研究  

Comparison on therapeutic effect between transcatheter arterial chemoembolization combined with percutaneous microwave coagulation therapy and percutaneous microwave coagulation therapy for hepatocellular carcinoma

作　　者：丁一[1] 曹智[2] 陆伟[2] 黄汝刚[2] 刘建勇[2] 

机构地区：[1]天津医科大学,天津300070 [2]天津市第二人民医院

出　　处：《滨州医学院学报》2013年第1期16-18,31,共4页Journal of Binzhou Medical University

摘　　要：目的比较TACE联合PMCT与单独使用PMCT治疗原发性肝细胞癌的近期疗效。方法将行介入治疗的原发性肝细胞癌患者随机分为两组:TACE联合PMCT治疗组(TP组)及PMCT治疗组(P组)。TP组患者接受TACE治疗后1～3周内行DSA检查结果决定是否行超声引导下PMCT治疗。对P组患者单独采用PMCT治疗。分别对两组患者术前、术后肝功能,血清甲胎蛋白(AFP)水平,肿瘤的改变情况,相关并发症及生存率进行比较。结果接受TACE联合PMCT治疗患者AFP值下降及肿瘤缩小程度较单独采用PMCT治疗明显;两组患者生存率存在显著差异(P<0.05)。结论 TACE联合PMCT治疗原发性肝细胞癌较单独使用PMCT治疗更有效。Objective Comparison on therapeutic effect between transcatheter arterial chemoembolization combined with pereutane- ous microwave coagulation therapy and percutaneous microwave coagulation therapy for hepatocellular carcinoma. Methods Patients were randomly divided into group TP and group P. Before and after therapy, patients＂ serum α-fetoprotein level （ AFP） ,responses of tumor, complications related to embolization and survive rates were analyzed between two groups. Results The AFP level and size of tumor in group TP were lower than those in group P （ P 〈 0.05）. There were significant statistical differences in the survival rate be- tween the two groups （ P 〈0. 05 ）. Conclusion The combination of PMCT and TACE is more effective for hepatocelluar carcinoma than PMCT alone.

关 键 词：肝细胞癌 经动脉栓塞化疗 经皮微波凝固治疗 

分 类 号：R735.7[医药卫生—肿瘤]