调节过程中人眼高阶像差的变化  

Changes in higher-order aberrations of the human eye during the accommodation process

作　　者：熊瑛[1] 余翔[2] 李婧[1] 王宁利[1] 薛丽霞[2] 李树宁[1] 卿国平[1] 凌宁[2] 

机构地区：[1]首都医科大学附属北京同仁医院北京同仁眼科中心北京市眼科学与视觉科学重点实验室,100730 [2]中国科学院光电技术研究所

出　　处：《中华眼视光学与视觉科学杂志》2013年第3期146-149,共4页Chinese Journal Of Optometry Ophthalmology And Visual Science

基　　金：国家科技部863计划项目导向课题（2006AA0224D2）;国家自然科学基金资助项目重点课题（60438030）

摘　　要：目的探讨生理性调节对人眼波前像差的影响。方法描述性研究。通过移动注视视标诱发调节，并在不同调节状态下采集眼波前像差。评估内容包括可诱发的调节幅度、比较调节幅度大于3D与调节幅度小于3D两组在调节放松状态下高阶像差的差异以及比较0D、1D、3D3种调节状态，在3．11mm和4．93mm两种瞳孔直径下，眼波前像差的变化特点。采用独立样本t检验和单因素方差分析处理数据。结果在本实验条件下可以实现诱发调节，最大调节幅度可达7．43D。调节幅度大于3D和小于3D两组被检者的高阶像差差异无统计学意义。在O～3D调节范围内．人眼高阶像差变化无统计学意义；但是在调节过程中位于Zernike多项式金字塔排布的中轴部位的第12项、第24项和第33项的变化具有统计学意义（F=3．799，P〈0．05）。结论调节过程中人眼高阶像差会产生补偿离焦的结构性变化。Objective To investigate the induced by physiological accommodation. Methods changes in ocular wavefront aberrations that were A descriptive study was adopted for this research and the different stages of ocular accommodation were induced by moving the visual target. At the same time, the value of wavefront aberrations was measured under different accommodative stages. These results were used to evaluate the induced amplitude and to compare the differences in higher- order aberrations for the groups with accommodative amplitudes greater than 3 D and less than 3 D under a relaxed state. In addition, the characteristic changes in wavefront aberrations for three different levels of accommodative demand （0 D, 1 D, 3 D） and between pupil diameters at 3.11 mm and 4.93 mm were evaluated and compared. The collected data was analyzed by independent t tests and an ANOVA. Results The induced accommodation was achieved under the present experimental conditions with a maximum amplitude up to 7.43 D. There was no statistical difference between the groups with amplitudes greater than or less than 3 D in terms of higher-order aberrations. With accommodation between the 0 D and 3 D range, the change in higher-order aberrations was not statistically significant. However, during the process of accommodation, the values of coefficients 12, 24 and 33 from the Zernike polynomial pyramid, which were all located on the axial of the pyramid, had statistically significant changes （Mini F=3.799, P〈0.05）. Conclusion When the human eye is in the accommodative mode, there are structural changes in higher order aberrations that compensate for the change in defocus.

关 键 词：调节 眼 波前像差 瞳孔直径 

分 类 号：R77[医药卫生—眼科]