白介素-1β与种植体周围炎的相关性实验研究  

Experiment study on relationship between IL-1β and peri-implantitis

作　　者：刘璐[1] 张巧红[2] 朱洪光[2] 高晓琳[1] 李效斐[1] 于会杰[1] 

机构地区：[1]潍坊医学院,在读硕士研究生261042 [2]潍坊人民医院

出　　处：《中国口腔种植学杂志》2013年第1期15-17,共3页Chinese Journal of Oral Implantology

摘　　要：目的:研究种植体周围龈沟液(PICF)中的IL-1β(白介素-1β)与种植体周围炎的相关性。方法:将受试种植体大致分为三组:A组轻度种植体周围炎25枚、B组重度种植体周围炎5枚、C健康组(对照组)16枚,用ELISA法检测各PICF中IL-1β的含量。结果:C组的PICF中未检测到IL-1β,而A、B组的PICF中可检测出IL-1β,且检出率与炎症程度成正相关。结论:IL-1β与种植体周围炎的发生具有相关性,可作为评价种植体周围炎程度的指标。Objective： To investigate the correlation of IL-1β in peri -implant crevicular fluid （PICF） and peri-implantitis. Methods： To divide the test implant into three groups, group A is mild peri-implanti- tis around 25 pieces, group B is severe peri-implantitis around 5 pieces, and group C is the health group （control group） around 16 pieces. IL-1β of PICF are all tested by ELISA. Results： IL-1β can be detected in PICF of group A and B, but cannot be found in group C. And the detection rate of IL- 1β is in positive correlation with inflammation indexes. Conclusion： The IL-1β must has relevance with peri-implantitis, and it could be used to evaluate the healthy condition of the peri-implantitis.

关 键 词：种植体周围炎 IL-1Β 牙种植体 ELISA法 实验研究 

分 类 号：R783.6[医药卫生—口腔医学]