奥乐V护牙剂对早期釉质龋再矿化作用的研究  

Effect of OHOLV on the remineralization of early enamel caries

作　　者：隋小玲[1] 刘源[1] 杨燃[1] 邹静[1] 

机构地区：[1]口腔疾病研究国家重点实验室,华西口腔医院儿童口腔科,四川大学,成都610041

出　　处：《华西口腔医学杂志》2013年第2期141-144,149,共5页West China Journal of Stomatology

基　　金：四川省科技支撑计划基金资助项目(2010SZ0102)

摘　　要：目的观察奥乐V护牙剂对早期釉质龋的再矿化作用。方法将50个牛牙釉质块建立人工龋模型后随机分为5组:奥乐V护牙剂组、GC护牙素组、氟化钠(NaF)组、奥乐V护牙剂+NaF组、去离子水(DDW)组,分别进入pH循环模型。采用显微硬度计测定各组标本脱矿前和pH循环后的釉质表面硬度值,扫描电镜观察各组再矿化后釉质表面形态结构的改变。结果各实验组经再矿化处理后其表面显微硬度均明显提高(P<0.001),奥乐V护牙剂组再矿化后其表面显微硬度低于NaF组(P<0.001),但与GC护牙素组间差异无统计学意义(P>0.05);再矿化后奥乐V护牙剂组釉质表面有较大颗粒沉积。结论奥乐V护牙剂具有促早期人工釉质龋再矿化的作用。Objective To observe the effect of OHOLV on the remineralization of early enamel caries. Methods Fifty bovine teeth with artificial early caries were divided into five groups randomly and treated with OHOLV, casein phosphopeptide amorphous calcium phosphate （CPP-ACP）, NaF, OHOLV＋NaF and distilled and deionized water（DDW） respectively. Then the teeth were subjected to the pH-cycling. The surface microhardness （SMH） of enamel before demineralization and after remineralization were measured by mierohardness detector and the histomorphologie changes of the enamel surface were compared by scanning election microscope （SEM）. Results The SMH of all the experimental groups increased significantly after remineralization（P〈0.001）. The SMH of the OHOLV group was lower than that of NaF group （P〈0.001）, while there was no significant difference between the OHOLV group and the CPP-ACP group （P〉0.05）. After remineralization, a large amount of comparatively large mineral particles deposited On the surface of the enamel treated with OHOLV. Conclusion OHOLV can promote the remineralization of the early enamel

关 键 词：奥乐V护牙剂 早期釉质龋 再矿化 

分 类 号：R781.1[医药卫生—口腔医学]