安徽地区283例慢性过敏性皮肤病斑贴试验结果分析  

Patch test results analysis of 283 cases of chronic dermatitis patients in Anhui

作　　者：刘蔚[1] 姚秀华[1] 张兰芳[1] 胡白[1] 

机构地区：[1]安徽医科大学附属省立医院皮肤科,安徽合肥230001

出　　处：《安徽医药》2013年第3期447-450,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的探讨慢性过敏性皮肤病患者常见的致敏原及其特点,为其防治提供依据。方法应用"瑞敏牌"斑贴试剂盒检测283例慢性过敏性皮肤病患者,对试验数据进行统计学分析和比较。结果 283例患者中有158例对20种致敏原中的1种或2种以上呈现阳性反应,总阳性率为55.83%。阳性率高的前5位过敏原依次为:硫酸镍(20.14%)、甲醛(14.49%)、氯化钴(13.43%)、Cl+Me-异噻唑(12.01%)、芳香混合物(10.95%)等。皮损位于躯干四肢者对甲醛阳性率最高(21.88%),唇炎对松香阳性率最高(10.64%)。性别、年龄间斑贴试验阳性率无明显差异。结论斑贴试验寻找慢性过敏性疾病致敏原简单可靠;不同部位皮损和不同病种的常见致敏原不同。Objective To detect and analyze the common allergens and the character of chronic allergic dermatitis,and to provide the basis for prevention and treatment of the disease.Methods 283 diagnosed cases of chronic allergic dermatitis were tested with a standardized patchtesting technique（Rei Min Pai）against contact allergens.The test data were analyzed by statistical methods and the results were compared with national monitoring results.Results 158 cases were allergic to at least one antigen in 20 kinds of standard series antigens.The total positive rate was 55.83%.The several antigens which caused the top 5 high positive rate were：nickel sulphate（20.14%）,formaldehyde（14.49%）,cobalt chloride（13.43%）,Cl＋Me-isothiazole（12.01%）,aromatic compounds（10.95%）.The most common allergen causing dermatitis of trunk and limbs was formaldehyde（21.88%）.The most common allergen causing cheilitis was colophony（10.64%）.There was no statistically significant difference between both sexes and also among different age groups.Conclusion Patch test is a reliable and simple method for looking for allergens in chronic allergic dermatitis.There are different allergens in diverse sick parts and also in diverse skin diseases.

关 键 词：斑贴试验 皮肤病 致敏原 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]