新型马来松香基双官能化合物的合成及其抑菌活性  

Synthesis and Fungicidal Activities of Novel Maleated Rosin-Based Difunctional Compounds

作　　者：董淑求[1] 段文贵[1] 岑波[1] 许雪棠[1] 韦有杰[1] 李龙生[1] 

机构地区：[1]广西大学化学化工学院,广西南宁530004

出　　处：《合成化学》2013年第2期178-184,共7页Chinese Journal of Synthetic Chemistry

基　　金：国家自然科学基金资助项目(31060100);广西自然科学基金重点资助项目(2010GXNSFD013013);广西自然科学基金资助项目(2010GXNSFA013040);广西大学科研基金资助项目(XBZ090120)

摘　　要：以松香为原料合成了马来松香(1);1经酰氯化、肼解和酰化反应制得马来松香双酰肼(4a～4g);以三氯氧磷为脱水剂,4a～4g关环合成了7个新型的马来松香基双官能化合物(5a～5g),其结构经1H NMR,13C NMR,IR和MS表征。生物活性测试结果表明,5a～5g对黄瓜枯萎病菌、苹果轮纹病菌、番茄早疫病菌、花生褐斑病菌和小麦赤霉病菌均有一定抑菌活性,尤其是对苹果轮纹病菌较好。Maleated rosin （1） was prepared from rosin. Maleated rosin-based dihydrazides （4a . 4g） were synthesized from 1 by acyl chlorization reaction, hydrazinolysis reaction and acylation reaction. Seven novel maleated rosin-based difunctional compounds （5a . 5g） were synthesized by cyclization of 4a - 4g in the presence of phosphorus oxychloride. The structures were characterized by 1H NMR, 13 C NMR, IR and MS. The preliminary bioassay tests indicated that 5a . 5g exhibited a certain fungi- cidal activities against Fusarium oxysporum f. sp. cucumerinum, Physalospora piricola, Alternaria sola- ni, Cercospora rachidicola and Fusarium graminearum, especially against Physalospora piricola.

关 键 词：马来松香 酰胺 噁二唑 合成 抑菌活性 

分 类 号：O626.24[理学—有机化学] O623.626[理学—化学]