空腹血糖对急性重症脑梗塞患者神经功能及短期预后的影响  

Effect of fasting blood glucose level on neurological function and short-term prognosis in patients with acute cerebral infarction

作　　者：段风梅[1] 焦燕[1] 朱沂[1] 

机构地区：[1]新疆维吾尔自治区人民医院神经内科,新疆乌鲁木齐830001

出　　处：《海南医学》2013年第5期661-663,共3页Hainan Medical Journal

摘　　要：目的探讨空腹血糖对急性脑梗塞神经功能及短期预后的影响。方法选取神经内科重症监护室连续住院的81例急性脑梗塞患者为研究对象。根据入院后首次空腹血糖≥7mmol/L定为空腹血糖增高组,空腹血糖<7mmol/L为空腹血糖正常组。检测患者血压、血脂、血清总蛋白(TP)、白蛋白(ALB)等指标,观察空腹血糖≥7mmol/L时患者的神经功能缺损及短期预后情况。结果空腹血糖增高组入院时NIHSS评分(10.71)及出院时NIHSS评分(8.73)均高于血糖正常组(入院时7.2,出院时4.85),P<0.05;空腹血糖增高组死亡率(16.7%)及预后不良发生率(25.0%)均高于空腹血糖正常组(死亡率为7.0%,预后不良发生率为21.1%),但差异无统计学意义。空腹血糖增高组营养不良发生率(62.5%)高于血糖正常组(35.1%),P<0.05。结论急性脑梗塞合并空腹血糖增高患者的神经功能缺损明显加重,营养不良发生率增加。Objective To find out the effect of fasting blood glucose level on neurological function and short-term prognosis in patients with acute cerebral infarction. Methods Eighty-one patients with acute cerebral in-farction were enrolled in Neurological Intensive Care Unit （NICU）. Based on the fasting blood glucose level, the pa-tients were divided into the increased group （≥7 retool/L） and the normal group （ 〈 7 mmol/L）. Blood pressure, blood lipids, total protein （TP）, and albumin （ALB） were detected. The neurological functional defects and short-term prog-nosis were observed when the fasting blood glucose level was higher than 7 mmol/L. Results The NIHSS scores at admission and discharge in the increased group （10.71 and 8.73） were significantly higher than those in the normal group （7.2 and- 4.85）, P〈0.05. The mortality rate and the incidence of poor prognosis were slightly higher in the in- creased group than the normal group, with no statistically significant difference. The incidence of malnutrition was sig-nificantly higher in the increased group （62.5%） than the normal group（35.1%）, P〈0.05. Conclusion There were ag-gravated neurological functional defects and higher incidence of malnutrition in the patients of acute cerebral infarc-tion with increased fasting blood glucose level.

关 键 词：急性脑梗塞 空腹血糖 预后 

分 类 号：R743.33[医药卫生—神经病学与精神病学]