炎症性肠病与精神心理因素相关性研究  

Correlation between Psychological Factors and Inflammatory Bowel Disease

作　　者：李敏丽[1] 瞿勇[1] 缪应雷[1] 

机构地区：[1]昆明医科大学第一附属医院消化内科,云南昆明650032

出　　处：《昆明医科大学学报》2013年第2期32-38,共7页Journal of Kunming Medical University

基　　金：国家自然科学基金资助项目(81260074)

摘　　要：目的探讨炎症性肠病患者出现焦虑、抑郁的相关影响因素,为伴有精神心理异常的IBD的患者进行抗焦虑抑郁及心理治疗提供理论依据.方法收集2010年12月至2011年12月昆明医科大学第一附属医院消化内科门诊及住院已确诊的IBD患者60例,正常对照60例,采用一般情况调查表、ZUNG焦虑自评量表(self-rating anxiety scale,SAS)、ZUNG抑郁自评量表(self-rating depression scale,SDS)、生活事件量表(life eventscale,LES)及社会支持评定量表(social support rating scale,SSRS)对IBD患者及正常对照进行评定.运用SPSS统计软件分析,P<0.05为差异有统计学意义.结果 (1)焦虑、抑郁发生率比较:焦虑发生率IBD组>正常对照组,两组比较P<0.05;IBD组抑郁发生率与正常对照比较P<0.01;(2)SAS、SDS评分结果显示:IBD组患者与正常对照比较P<0.01;(3)LES、SSRS评分结果显示:IBD组与正常对照比较负性事件分差异有统计学意义(P<0.01).结论 (1)IBD患者焦虑、抑郁发生率高于正常人;(2)负性生活事件对IBD、患者精神心理有重要影响;(3)生活事件、社会支持度与IBD患者精神心理变化密切相关;(4)临床实践中应关注IBD患者的心理状态,对有明显焦虑和抑郁的患者应给予相应的干预措施.Objective To study the relevant factors of anxiety and depression in patients with IBD, in order to provide theoretical basis of the anti-anxiety depression and psychological treatments for IBD patients with psychological abnormalities. Methods 60 patients with IBD from December 2010 to December 2011 were collected in Department of Gastroenterology in the First Affiliated Hospital of Kunming Medieal University. During the same period, 60 patients with IBD and 60 healthy controls were collected. ZUNG self-rating anxiety scale, ZUNG self-rating depression scale, life event scale and social support rating scale were used to evaluate the psychological condition of all patients. All scores were statistically analyzed by SPSS, P〈0.05 was considered have statistic difference, P〈O.01 was considered to have significant statistic difference. Results （1） The comparison of incidence of anxiety and depression： IBD group〉healthy controls （P〈0.05） The incidence of depression in IBD groups was higher than healthy controls （P〈0.01） （2） Results of self-rating anxiety scale, self-rating depression scale showed that there statistieally significant difference between IBD group and healthy controls （P〈 0.01） （3） Life event scale, social support rating scale results showed that： there was statistically significant difference in negative events score between IBD groups and healthy controls （P〈0.01） . Conclusions （1） The incidence of anxiety and depression in IBD patients is higher than the normal healthy people. （2） Negative life events have an important impact on the psychological condition of IBD patients. （3） Life events and social support are closely related to psychological changes of IBD patients. （4） IBD patient＇s psychological state should be concerned in clinical practice and appropriate interventions should be given if there is a clear anxiety and depression in the patients.

关 键 词：炎症性肠病 焦虑 抑郁 精神心理因素 

分 类 号：R574[医药卫生—消化系统]