儿童注意缺陷多动障碍与血清叶酸水平关系  

Relationship between children with attention deficit hyperactivity disorder and folic acid in serum

作　　者：高磊[1] 关明杰[1] 孙宇[1] 曹瑞珍[1] 王未来[1] 

机构地区：[1]包头医学院公共卫生学院,内蒙古014040

出　　处：《中国学校卫生》2013年第3期335-336,339,共3页Chinese Journal of School Health

基　　金：内蒙古自然科学基金项目(2010MS1110);内蒙古高教厅科学基金项目(NJ04022)

摘　　要：目的探讨儿童血清叶酸与注意缺陷多动障碍之间的关系,为指导儿童合理补充维生素提供科学依据。方法对包头市某小学全体在校生进行筛查,以筛查出的78名注意缺陷多动障碍儿童为病例组,选择年龄、性别一致且没有血缘关系的87名儿童为对照组,统一进行专业采血,采用化学发光免疫分析法进行血清叶酸的测定。结果注意缺陷多动障碍组儿童与正常儿童组间血清叶酸水平差异无统计学意义;评价Conners教师问卷及父母问卷各因子与血清叶酸的关系,结果显示在焦虑方面血清叶酸不足组儿童的得分明显高于血清叶酸正常组(P<0.05)。相关分析显示,焦虑与血清叶酸值呈负相关(r=-0.166,P<0.05)。结论血清叶酸对儿童注意缺陷多动障碍的发生没有直接影响,但与儿童焦虑情绪的发生有密切的关系。Objective To explore the relationship between serum folic acid and children with attention deficit hyperactivity disorder,and to provide the scientific basis for rational guidance of vitamin supplements of children.Methods Screening of all students in a primary school in Baotou City,in order to find children with attention deficit hyperactivity disorder,and choose the reasonable control children,using the chemiluminescence immunoassay for serum folic acid determination.Results No significant differences of serum folic acid levels were found between the group of children with attention deficit hyperactivity disorder and the group of normal children.The results showed that the anxiety aspects of inadequate group scored significantly higher than normal group,the correlation analysis showed that anxiety and serum folic acid values was a negative correlation（r=-0.166,P＆lt;0.05）.Conclusion Serum folic acid has no direct impact on the occurrence of children with attention deficit hyperactivity disorder,but it has closely related with the occurrence of children’s anxiety.

关 键 词：注意力缺陷障碍伴多动 血清 叶酸 儿童 

分 类 号：G477[文化科学—教育学] R591[文化科学—教育技术学]