杂环取代-1,2-二苯基烯类化合物的合成及抗癌活性研究  

Synthesis and Anticancer Activities of Heterocyclic ring Substituted 1,2-Diphenylethylene

作　　者：刘波[1] 朱娜[1] 崔景荣[1] 雷小平[1] 

机构地区：[1]北京大学药学院,北京100083

出　　处：《中国医药工业杂志》2000年第9期391-394,共4页Chinese Journal of Pharmaceuticals

基　　金：北京医科大学天然药和仿生药国家重点实验室资助!课题 ( 99-客 12 )

摘　　要：报道了 13个新化合物的合成 ,其中 9个是杂环取代 - 1,2 -二苯基烯类化合物。实验表明它们对人鼻咽癌 (KB)和人宫颈癌 (He L a)细胞增殖均有一定的抑制作用。Thirteen new compounds were synthesized, in which nine heterocyclic ring substituted 1,2 diphenylethylenes are target compounds. They were tested for their inhibitory activity to KB and HeLa cancer cells and exhibited some positive effect.\;

关 键 词：杂环取代 二苯基烯类 合成 抗癌活性 

分 类 号：R979.1[医药卫生—药品] R914.5[医药卫生—药学]