肺内大肿块呼吸动度的测量与分析  

Measurement and analysis of the lung large tumor respiratory movements of large lung tumors

作　　者：王卫军[1] 马少林[1] 王艳丽[1] 李润浦 

机构地区：[1]河北省保定市第二中心医院肿瘤科,072750

出　　处：《肿瘤研究与临床》2013年第3期181-183,共3页Cancer Research and Clinic

摘　　要：目的分析肺内肿瘤因呼吸导致运动的影响因素，寻找运动度大的肿瘤特征。方法分别在平静吸气后屏气、平静呼气后屏气状态下接受CT扫捕的目市内肿瘤患者30例，肺内可测量病灶30个。南同一位医生在两个时相的CT数据上勾画肿瘤大体肿瘤体积（GTV），分别测量GTV中心层而前后内外界在呼吸周期中左右、前后方向的运动幅度；肿瘤最上层及最下层上下方向的运动幅度。对与运动度可能相关的临床变量和解削学因素进行讨论：结果肺内大肿瘤位置相对同定，肿瘤中心层而各方向动度多数在3～5mm，只有2例患者肿瘤的各个方向运动幅度〉5Hmm，均位于胸腔中下部及中后部，粘连系数较低，体积较小，为上下方向运动。95％的肺内肿瘤中心层面的运动幅度在上下方向〈3．8mm，前后方向〈5．8mm，左右方向〈1．1mm。结论呼吸导致的肺内肿瘤运动度受肿瘤位置、体积及粘连程度等因素影响，但运动幅度较小，下后带运动度最大，主要发生在上下方向。Objective To measure intrapulmonary tumor motion due to breathing and analyze the impact factors and characteristics of the respiratory movement of large lung tumors. Methods CT scan was conducted in 30 patients with puhnonary caneer, in the calm inspiratory breath-holding and calm breath after breath-hohiing state. The tumor GTV in the two phases was recorded. The motion range in the left-right and antero-posterior directions in the GTV center level during the respiratory cycle was measured. The motion range of uppermost and lowermost layer of the tumor f}＇om top to bottonl was also recorded. The clinical variables and anatomical factors associated with the degree of motion were analyzed. Results The position of large lung tumor was relatively fixed, and the motion range was 3-5 ram, but 2 patients movement was found more than 5 ram. The two tumors were located in the lower part and the rear of the chest with low adhesion coefficient and smaller vertical dh＇ection of movement. 95 % of motion range of the intrapulmonary tumot：s were under 3.8 mm in the vertical direction, under 5.8 mm in the front-rear direction, and under 1.1 mm in the left-right direction. Conclusion The movement of lung tumors caused by respiratory, are influenced by tumor location, volume, and other factors such as the degree of adhesion, but the motion ranges are lower. The motion of lower rear tumors mainly occur in the vertical direction with the maximum range. [Key words]

关 键 词：肺肿瘤 放射疗法 

分 类 号：R734.2[医药卫生—肿瘤]