CTA观察肿瘤滋养动脉变化对肝癌TACE术疗效评价的意义  

作　　者：周春献[1] 陈超[1] 徐东风[1] 韩旭[1] 陆海林[1] 蒲俊舟[1] 

机构地区：[1]南通大学附属吴江医院,215200

出　　处：《浙江临床医学》2013年第4期456-458,共3页Zhejiang Clinical Medical Journal

摘　　要：目的探索CT血管成像技术（CTA）滋养动脉变化对原发性肝细胞癌（HCC）化疗栓塞术（TACE）疗效评价的意义.方法38例不能手术切除的HCC患者于术前1周内和接受2次TACE治疗4周后行螺旋CT增强扫描,并作3D图像重建,比较手术前后肿瘤滋养动脉变化,以消失、变细、无明显变化、增粗、出现新生血管分级,以改良RECIST标准评价肿瘤缓解程度.结果5例达到CR标准,肿瘤滋养动脉均消失;24例达到PR标准,超过半数的肿瘤滋养动脉消失或明显变细;9例达到SD标准,肿瘤滋养动脉无明显改变或部分变细.结论 CTA是评价TACE治疗HCC疗效的可行方法.Objective To explore the ability of computed tomography angiography in the response evaluation of transarterial chemoembolization for HCC. Methods A total of thirty-eight consecutive patients with unresectable HCC received two cycles of TACE. Unenhanced and contrast-enhanced CT examinations of the upper abdomen were executed one week before the first treatment and four weeks after the second treatment. The feeding arteries were reconstructed by maximum intensity projection and volume rendering with the preoperative and postoperative CT data of arterial phase. The change of the tumor feeding artery was described with disappeared,narrowed,unchanged,enlarged,new artery emerged. Tumor response was evaluated according to the modified RECIST. Results Five patients got a CR. Each feeding vessel was well occluded and couldn＇t be recognized in CTA. Twenty-four patients got a PR. In this group,more than half of their feeding vessels disappeared or narrowed obviously. The rest of nine patients with four lesions got a SD,whose feeding vessel unchanged or narrowed partly. Conclusion The changes of feeding arteries by CTA is a feasible and tangible method for evaluating the treatment response to transarterial chemoembolization therapy for HCC.

关 键 词：肝细胞癌 CT血管成像技术 化疗栓塞术 

分 类 号：R735.7[医药卫生—肿瘤]