人乳头瘤病毒感染与宫颈癌的研究进展  

Research Advancement of Relationship between Human Papillomavirus and Cervical Cancer

作　　者：刘英华[1] 陈瑛[1] 

机构地区：[1]南京医科大学附属苏州医院生殖与遗传中心,江苏苏州215002

出　　处：《现代生物医学进展》2013年第5期973-976,共4页Progress in Modern Biomedicine

基　　金：江苏省"十二五"科教兴卫工程医学重点人才资助项目(RC2011036)

摘　　要：宫颈癌是一种严重危害女性健康的恶性肿瘤,其发病率较高,位居女性恶性肿瘤的第二位,仅次于乳腺癌。流行病学治疗显示,99%的宫颈癌患者均感染高危型人乳头瘤病毒(Human papillomavirus,HPV),HPV是宫颈癌的首要病因。近年来,HPV分型检测技术的发展十分迅速,在宫颈癌筛查中与细胞学检测联合应用,对子宫颈病变的早期发现和预防有很重要的意义,可以提高诊断的敏感性,预防宫颈癌的发生和改善宫颈癌患者的预后。本文拟对HPV感染的检测方法与宫颈癌的研究进展做一综述。Cervical cancer is a malignant tumor,and it has relatively high incidence,second only to breast cancer.Epidemiological treatment study showed that,99% of the patients with cervical cancer are all infected with high-risk human papillomavirus which is the primary cause of cervical cancer.The HPV genotyping technology has developed rapidly in recent years,HPV detecting and genotyping combined with cytology in the cervical cancer screening is very important for early detection and prevention of cervical lesions,which not only can improve the sensitivity,but also can greatly prevent the incidence of cervical cancer and improve the prognosis of patient with cervical cancer.We briefly review the detection methods of HPV infection and the progress of cervical cancer.

关 键 词：人乳头瘤病毒 宫颈癌 分型检测技术 癌前病变 

分 类 号：R711.74[医药卫生—妇产科学]