应用事件相关电位N400用于脑卒中后失语症患者康复治疗的作用  

The effect of event-related potentials N400 in rehabilitation for patients with post-stroke aphasia

作　　者：申丽红[1] 张冰[2] 赵俊鹏[3] 

机构地区：[1]河北联合大学外国语学院,河北省唐山063000 [2]河北联合大学附属人民医院康复科 [3]河北联合大学基础医学院,河北省唐山063000

出　　处：《中国基层医药》2013年第8期1125-1126,共2页Chinese Journal of Primary Medicine and Pharmacy

基　　金：河北省唐山市科学技术研究与发展计划指令性项目（12140209A-8）

摘　　要：目的探讨脑卒中后失语症患者应用事件相关电位N400的意义，为其在临床应用提供理论基础。方法对29例脑卒中后失语症患者（失语组）和58例脑卒中后元失语症患者（对照组）进行事件相关电位N400检查，比较两组N400的潜伏期和波幅。结果N400差异波潜伏期失语组较对照组时间长，波幅较对照组大，且差异有统计学意义（均P〈0．05）。结论N400用于检测脑卒中后失语症患者语言功能障碍程度有一定的作用。Objective To explore the siqnificance of event related potential（ERP） N400 on stroke patients with aphasia and provide theoretical basis for clinical operations. Methods 29 stroke patients with aphasia（ aphasia group） and 58 stroke patients without aphasia（ control group） were selected, which were examined with N400. The latency and amplitude of N400 were compared between the two groups. Results The difference waves＇ latency and amplitude of aphasia group were longer and higher than those of control group. The difference had statistical significance （ all P 〈 0.05）. Conclusion N400 is a significant marker for the language disturbance of aphasia patients.

关 键 词：脑卒中 失语症 事件相关电位 

分 类 号：R743.3[医药卫生—神经病学与精神病学]