慢性肝病患者脾硬度值与肝硬度值的相关分析  

Spleen stiffness measurement and liver stiffness measurement in patients with chronic liver diseases

作　　者：梁宁[1,2] 韩涛[1,2,3,4] 刘芳[2] 李莹[2] 哈福双[1,2] 聂新华[1,2] 

机构地区：[1]天津医科大学第三中心临床学院,天津300170 [2]天津市第三中心医院 [3]天津市人工细胞重点实验室 [4]天津市肝胆疾病研究所

出　　处：《山东医药》2012年第45期4-6,10,共4页Shandong Medical Journal

基　　金：艾滋病和病毒性肝炎等重大传染病防治国家科技重大专项(2012ZX10002004-011);天津市科委基金资助项目(12JCYBJC17300)

摘　　要：目的研究慢性肝病患者脾脏硬度(SSM)值与肝脏硬度(LSM)值的相关性。方法选择200例慢性肝病患者,其中肝硬化组120例,肝炎组80例。采用瞬时弹性成像技术检测两组SSM及LSM程度,并对其SSM值和LSM值进行相关分析。结果肝硬化组、肝炎组的SSM值与LSM值均有显著相关性(r分别为0.377、0.314,P分别为0.000、0.005)。结论慢性肝病患者的SSM值与LSM值显著相关,临床联合检测SSM及LSM,可全面地评价慢性肝病患者的病情。Objective To investigate the correlation of spleen stiffness measurement （SSM） and liver stiffness meas- urement （LSM） in patients with chronic liver diseases. Methods 200 patients with chronic liver diseases were chosen, containing 120 patients with cirrhosis and 80 patients with hepatitis. Spleen stiffness measurement and liver stiffness meas- urement were determined by Fibroscan, then the correlation between SSM and LSM was analysed. Results In the patients with cirrhosis or hepatitis, there were both significant correlations between SSM and LSM （ r = 0. 377, P = 0. 000 ; r=0.314, P =0. 005 ）. Conclusion In patients with chronic liver diseases, there is a significant correlation between SSM and LSM, and their combinative detection could assess of disease condition of the patients with chronic liver diseases more comprehensively and synthetically.

关 键 词：肝脏疾病 肝硬化 肝炎 瞬时弹性成像系统 脾脏硬度值 肝脏硬度值 

分 类 号：R575.2[医药卫生—消化系统]