上消化道息肉临床特征分析2376例  

Clinical characteristics of upper gastrointestinal tract polyps:An analysis of 2 376 cases

作　　者：刘婉薇[1] 马娟[1] 余莲英[1] 沙卫红[1] 王启仪[1] 

机构地区：[1]广东省人民医院(广东省医学科学院)消化科,广东省广州市510080

出　　处：《世界华人消化杂志》2013年第8期709-713,共5页World Chinese Journal of Digestology

基　　金：国家自然科学基金资助项目;No.81001112;广州市科技局珠江科技新星基金资助项目;No.2012J2200019~~

摘　　要：目的:回顾性分析我院胃十二指肠息肉的临床学特征,以期指导临床诊疗.方法:收集近十年来我院胃镜确诊上消化道息肉的患者,记录一般临床资料,分析上消化道息肉部位、病理类型、幽门螺杆菌(Helicobacter pylori,H.pylori)感染、性别、年龄、伴随症状等临床特征.结果:共收集2376例上消化道息肉患者,男691例(29.08%)和女1685例(70.92%);68.01%(1616/2376)的年龄>40岁者发生上消化道息肉;41.96%(997/2376)的患者主要症状为上腹部不适,39.26%(932/2376)的患者反复上腹痛;所有上消化道息肉发生部位为食管35例(1.47%)、贲门211例(8.88%)、胃底体1530例(64.39%)、胃窦275例(11.57%)、十二指肠290例(12.21%)、残胃35例(1.47%).发生于胃窦和贲门的息肉伴随较高的H.pylori阳性率,分别为41.44%和33.07%(P<0.05).结论:上消化道息肉多为良性病变,好发于40岁以上患者,女性多见,伴随症状多为上腹不适,息肉病理类型与息肉发生部位有一定关系.胃底体息肉以胃底腺息肉为主,食管、胃窦、十二指肠和残胃的息肉以黏膜萎缩的息肉样改变为主要病理表现.H.pylori感染者上消化道息肉容易发生在贲门和胃窦.AIM： To analyze the clinical characteristics of esophagus-gastro-duodenal polyps. METHODS： Clinical data for patients with esophagus-gastro-duodenal polyps who were treated at our hospital over the past decade were retrospectively analyzed. The sites and histologi- cal types of polyps were identified to investigate the association of the polyps with factors includ- ing Helicobacter pylori （H. pylori） infection, gen- der, age, and epigastric symptoms. RESULTS： A total of 2 376 patients with polyps were enrolled, including 691 （29.08%） males and 1 685 （70.92%） females. 68.01% （1 616/2 376）of patients were more than 40 years old. Main symptoms included epigastric upset （41.96%, 997/2 376） and epigastric pain （39.26%, 932/2 376）. The polyps were mainly located in the corpus and body （64.39%）, duodenum （12%）, antrum （11.57%）, cardiac （8.88%） and other sites （14.09%）. Patients with antral polyps or cardic polyps had a higher frequency of H. pylori infec- tion （41.44% and 33.07%）. CONCLUSION： Upper gastrointestinal tract pol- yps are usually benign and tend to occur in pa- tients more than 40 years old and females. Main symptom is epigastric upset and main patholog- ical type is fundic gland polyps. H. pylori infec- tion might be associated with the development of antral polyps and cardiac polyps.

关 键 词：上消化道 息肉 病理类型 幽门螺杆菌 

分 类 号：R735[医药卫生—肿瘤]