自体角膜缘干细胞移植联合羊膜移植治疗复发性翼状胬肉  

Observation of autologous limbal stem cell transplantation combined with amniotic membrane transplantation in the treatment of recurrent pterygium

作　　者：王亚丽[1] 但汉东[1] 宋秀胜[1] 

机构地区：[1]武汉大学恩施临床学院恩施州中心医院眼科中心,中国湖北省恩施市445000

出　　处：《国际眼科杂志》2013年第4期832-833,共2页International Eye Science

摘　　要：目的:探讨自体角膜缘干细胞移植联合羊膜移植治疗复发性翼状胬肉的手术方法及临床疗效。方法:回顾性分析本院2010-01/2011-06采用自体角膜缘干细胞移植联合羊膜移植术治疗的复发性翼状胬肉患者病历资料。记录患者一般情况、病史、眼部检查、手术方式、术后角膜创面修复时间、角膜体征及胬肉复发情况。结果:共30例32眼,术后随访12～24(平均16)mo,30眼术后角膜透明或仅遗留少许云翳,无新生血管长入,复发2眼,复发率约6%。结论:自体角膜缘干细胞移植联合羊膜移植术是治疗复发性翼状胬肉安全有效的手术方法,值得临床推广。AIM： To investigate the method and observe effectiveness of autologous limbal stem cell transplantation combined with amniotic membrane transplantation in the treatment of recurrent pterygium. METHODS： Medical records of all patients with recurrent pterygium treated by autologous limbal stern cell transplantation combined with amniotic membrane transplantation from January 2010 through June 2011 were retrospectively analyzed, and the recurrent rate was observed. RESULTS： Totally 30 cases （32 eyes） were analyzed. The followed up time was 12 to 24 months, mean 16 months. In all eyes, 30 were transparent or only left a little corneal nebula, without new blood vessels, recurrence occurred in 2 eyes, and the recurrent rate was 6%. CONCLUSION ： Autologous limbal stem cell transplantation combined with amniotic membrane transplantation is a safe and effective method for recurrent pterygium.

关 键 词：复发性翼状胬肉 自体角膜缘干细胞移植 羊膜移植 

分 类 号：R779.6[医药卫生—眼科]