沈阳市城区2000～2009年女性乳腺癌发病趋势分析  

Incidence Trend of Female Breast Cancer in Urban Shenyang from 2000 to 2009

作　　者：耿丹[1,2] 李恂[3] 时景璞[1] 陈建平[3] 孙丽华[4] 吴晓梅[1] 张娜[1] 于慧会[1] 蔡云飞[1] 

机构地区：[1]中国医科大学附属第一医院临床流行病学教研室,沈阳110001 [2]辽宁省人民医院,沈阳110013 [3]沈阳市疾病预防控制中心,沈阳110031 [4]辽宁省肿瘤医院,沈阳110001

出　　处：《中国循证医学杂志》2013年第4期400-403,共4页Chinese Journal of Evidence-based Medicine

摘　　要：目的探讨2000～2009年沈阳市城区女性乳腺癌发病率、年龄分布及变化趋势。方法收集2000～2009年沈阳市疾控中心肿瘤登记报告系统登记的女性乳腺癌发病资料,采用SPSS 16.0软件对乳腺癌发病率、标化发病率进行分析。发病趋势采用χ2趋势检验和线性回归分析。结果 2000～2009年沈阳市城区女性乳腺癌年均粗发病率46.03/10万,年均标化发病率35.63/10万,10年间上升了160.41%和109.39%,平均每年递增11.22%和8.56%。粗发病率和标化发病率均呈上升趋势,差异有统计学意义(P<0.001)。50～64岁年龄组发病率呈直线上升趋势,10年上升271.97%,平均每年递增15.72%。经χ2趋势检验及线性回归分析,差异均有统计学意义(χ2=276.743,P=0.000;y=–22 355.560+11.205x,P=0.000)。结论沈阳市城区女性乳腺癌发病率呈上升趋势,并且有发病低龄化,50～64岁年龄组较多发的特点。Objective To explore the incidence, age distribution and change tendency of female breast cancer in urban Shenyang from 2000 to 2009. Methods The incidence data of female breast cancer recorded in Shenyang Center for Disease Control and Prevention from 2000 to 2009 were collected, and the incidence and standardized incidence of breast cancer were analyzed by using SPSS 16.0 software. The incidence trend was analyzed by means of X2 trend test and linear regression. Results The annual average crude incidence rate of female breast cancer in urban Shenyang from 2000 to 2009 was 46.03/100 000, while the annual average standardized incidence rate was 35.63/100 000, increased by 160.41% and 109.39% respectively during past 10 years, and the annual average increase was 11.22% and 8.56%, respectively. Both crude incidence rate and standardized incidence rate were in increasing trends with statistical significance （P〈0.001）. The crude incidence rate of the female at age of 50-64 showed a perpendicular rise trend, increased by 271.97%, and the annual average increase was 15.72%. The X2 trend test and linear regression showed a significant difference （X2=276.743, P=0.000; y= -22 355.560＋ 11.205x, P=0.000）. Conclusion The incidence of female breast cancer in urban Shenyang tends to rise with a vounger-a^ed trend, and the female at a^e of 50-64 are commonly affected

关 键 词：女性乳腺癌 发病率 流行病学调查 

分 类 号：R737.9[医药卫生—肿瘤]