^18F—FDG PET／CT诊断多发癌的价值  

Value of ^18F-FDG PET/CT in the diagnosis of multiple primary malignant neoplasms

作　　者：王胜军[1] 杨卫东[1] 赵小虎[1] 全志永[1] 易婧薇[1] 马晓伟[1] 李桂玉[1] 杨治平[1] 汪静[1] 

机构地区：[1]第四军医大学西京医院核医学科,西安710032

出　　处：《国际放射医学核医学杂志》2013年第2期96-99,共4页International Journal of Radiation Medicine and Nuclear Medicine

摘　　要：目的探讨^18F-FDG PET／CT在多发癌诊断中的价值。方法回顾性分析5822例疑似肿瘤患者，均行^18F-FDG PET／CT全身检查，经过活检或手术证实为多发癌患者32例。以病理结果作为金标准，以PET平均标准化摄取值（SUV一）≥2．5且CT上有形态学改变者作为PET／CT判断恶性肿瘤的标准，计算PET／CT诊断多发癌的灵敏度和准确率。结果本组患者中多发癌的发生率为0．55％，其中，双发癌30例、三发癌2例，共66个原发灶。32例多发癌的66个原发灶的SUVmax的平均值为6．68±3．61。PET／CT诊断多发癌原发灶真阳性为58个，假阴性为8个。PET／CT诊断多发癌的灵敏度为87．9％，准确率为87．9％。结论^18F-FDG PET／CT全身检查诊断多发癌具有较大价值。Objective To explore the value of ^18F-FDG PET/CT in diagnosis of multiple primary malignant neoplasms. Methods Five thousand eight hundred and twenty-two patients with suspected tumors were retrospectively reviewed. All cases underwent ^18F-FDG PET/CT and 32 patients were confirmed with muhiple primary malignancies by biopsy or resection. Mean standardized uptake value （SUVmax） was calculated and SUVmean≥2.5 and abnormal morphological changes on CT were used as a standard to diagnose a malignant tumor. The sensitivity and accuracy of PET/CT in diagnosis of multiple primary maligant neoplasms were calculated. Results The incidence rate of multiple primary malignant neoplasms was 0.55%. Double primary malignant neoplasms were in 30 cases and triplicate primary malignant tumors were in 2 cases. There were 66 malignant tumor lesions. The average of SUV in 66 malignant tumor lesions was 6.68±3.61. The results of PET/CT were 58 true positive lesions and 8 false negative lesions. The sensitivity and accuracy of ^18F-FDG PET/CT in diagnosis of multiple primary malignant neoplasms were 87.9% and 87.9% respectively. Conclusion ^18F-FDG PET/CT whole body scan has an important value in the diagnosis of multiple primary malignant neoplasms.

关 键 词：肿瘤 正电子发射断层显像术 体层摄影术 X线计算机 氟脱氧葡萄糖F18 

分 类 号：R730.44[医药卫生—肿瘤]