副肿瘤性肢端角化症1例并文献复习  

Acrokeratosis Paraneoplastica (Bazex Syndrome) : A Case Report and Literature Review

作　　者：张更建[1] 袁伟[1] 张信江[1] 王磊 

机构地区：[1]遵义医学院附属医院皮肤科,贵州遵义563000 [2]贵州石阡县医院,贵州石阡555100

出　　处：《中国皮肤性病学杂志》2013年第4期400-401,共2页The Chinese Journal of Dermatovenereology

摘　　要：患者男,38岁。双足背部褐色斑块并上覆灰白色鳞屑半年。皮损组织病理示:角化过度,颗粒层增厚,棘层肥厚,表皮呈乳头瘤样增生。真皮乳头层血管周围少量淋巴细胞浸润,真皮深层及皮下脂肪组织未见异常。随访4年时胃镜检查证实为食管癌。诊断:副肿瘤性肢端角化症。文中并对本病进行相并文献复习。A 38-years-old male, who had presented with brown plaque and gray scales on double dorsal feet for half a year. The histopathology of the skin lesion showed that epidermis was hyperkeratosis, granular layer, acanthosis, papillomatosis . There were a few lymphoeytes infiltrated around the blood vessels in dermal papilla layer. The deep dermis and subcutaneous fat tissues showed no abnormalities. After 4 years traeking observation, This patient was confirmed with esophageal cancer. Diagnosis was acrokeratosis paraneoplastiea. Moreover, we also reviewed the literature related to bazex syndrome.

关 键 词：肢端角化症 副肿瘤性 

分 类 号：R739.5[医药卫生—肿瘤]