不同加载条件下国产微螺钉种植体的支抗稳定性及组织学表现  

Stability and histological manifestation of microscrew implants under various loadings in rabbits

作　　者：曾晨光[1,2] 周彦恒[1] 林久祥[1] 丁鹏[1] 

机构地区：[1]北京大学口腔医学院正畸科,北京100081 [2]天津市开发区泰达医院口腔科,天津300457

出　　处：《吉林大学学报（医学版）》2013年第2期300-303,429,共4页Journal of Jilin University：Medicine Edition

基　　金：教育部高等学校博士点专业基金资助课题(20050001111)

摘　　要：目的:研究不同载荷下微型种植体的稳定性及种植体骨界面组织学表现,为其成功应用于临床提供理论依据。方法:将微型螺钉种植体(长度7mm,直径1.4mm)植入兔的胫骨,共植入种植体120枚。将其分成4组,每组30枚。在种植体植入后即刻分别对种植体施加0、150、300及450g的载荷,加载时间为20周。加载结束后检查种植体是否发生移位、松动和脱落,同时观察种植体骨结合界面组织学表现。结果:所有种植体均保持稳定,未发生松动和脱落。其中,450g组加载前后位移减小了0.60mm(P<0.05),而其他力值组加载前后位移也有所减小,0g组,0.09mm;150g组,0.20mm;300g组,0.16mm,差异均无统计学意义(P>0.05)。组织学观察,0g组和150g组种植体骨结合界面主要发生在骨皮质区,300g组种植体骨结合界面明显增宽,450g种植体骨结合界面进一步增宽,几乎发生在种植体全长。结论:种植体在一定载荷范围下可以保持稳定,当载荷达到一定程度,种植体可以发生位移。随着载荷的增加,种植体与骨结合程度亦加强。Objective To evaluate the stability and histological manifestation at implant-bone interface of the microscrew implants under various loadings and to provide the theoretical basis for the clinical treatment.Methods Microscrew implants（length 7 mm,diameter 1.4 mm） were implanted in the tibae of the rabbits,120 in total,and they were divided into 4 groups,30 in each group.After implantation the implants were loaded immediately with 0,150,300 and 450 g by NiTi coil.The loading period was 20 weeks.After the experiment the rabbits were sacrificed and the displacement of the implants were measured and peri-implant tissues were analyzed histologically.Results The average displacements of the implants in 0 g group,150 g group and 300 g group were very small,they were 0.09,0.20,and 0.16 mm;the difference had no significant difference（P0.05）.The average displacement of the implants in 450 g group was decreased（0.60 mm）,and the difference of displacement before and after loading was significant（P0.05）.The implant-bone interface in 0 g group and 150 g group were similar,mainly in the cortical bone.The implant-bone interface in 300 g group was much wider.And the interface in 450 g group almost contained all the implants.Conclusion The implants are stable with no displacement under certain amount of loading.Although microscrew is stable,it will have some displacement in some conditions.The implant-bone interface becomes longer with the increasing of loading.

关 键 词：种植体 支抗 动物实验 正畸 

分 类 号：R783.5[医药卫生—口腔医学] R-332[医药卫生—临床医学]