强迫障碍与惊恐障碍注意功能的对照研究  

A control study of attention deficit between obsessive-compulsive disorder and panic disorder

作　　者：吴东辉[1,2] 胡赤怡[1] 林雄标[1] 刘哲宁[3] 

机构地区：[1]深圳市精神卫生中心老年精神科,518020 [2]深圳市心理健康实验室 [3]长沙中南工业大学湘雅二院精神卫生

出　　处：《临床精神医学杂志》2013年第2期79-81,共3页Journal of Clinical Psychiatry

基　　金：深圳市科技局三项经费资助项目(200004035);深圳科技计划项目(201002136;JH200507120898A)

摘　　要：目的:探讨强迫障碍患者与惊恐障碍患者注意功能的特征。方法:采用倒行掩蔽测验(BMT)和连续操作测验(CPT)分别对强迫障碍患者、惊恐障碍患者和健康对照者3组各38例评估其注意的激活度、选择性注意和维持注意功能,以Maudsley强迫障碍症状问卷和Yale-Brown强迫量表对强迫患者评定其强迫症状严重程度。结果:掩蔽时间分别为30ms和50ms时,强迫障碍患者组的BMT正确数显著低于正常对照组(P均<0.05);无掩蔽时,两组BMT正确数差异无统计学意义;不同情境下,两组CPT正确数之间的差异无统计学意义。惊恐障碍患者在不同掩蔽的BMT正确数、不同情境下的CPT正确数与对照组相比,均无明显差异。掩蔽时间为30ms和50ms,强迫障碍患者组的BMT正确数[(5.6±2.5)和(9.2±4.1)]显著低于惊恐障碍组[(7.6±4.2)和(12.1±4.3)],(P均<0.05);而无掩蔽时,两组BMT正确数以及3种情境下的CPT正确数差异无统计学意义。强迫障碍患者的BMT正确数与Maudsley强迫障碍状问卷、Yale-Brown强迫行为和强迫思维量表的得分无显著相关性。结论:强迫障碍患者可能存在明显的选择性注意受损,而惊恐患者的注意功能无明显受损。Objective： To explore the attention deficit of patients with obsessive-compulsive disorder and patients with panic disorder. Method：This study included 38 patients with obsessive-compulsive disorder,38 patients with panic disorder and 38 sex-age-and education-matched control subjects.All subjects were used backward masking test（BMT） and continuous performance test （CPT） to evaluate vigilance of attention,selective attention and sustained attention.Patients with panic disorder or obsessive-compulsive disorder who were never treated.Patients with obsessive-compulsive disorder were assessed by Maudsley obsessional-compulsive inventory（MOCI） and Yale-Brown obsessive-compulsive scale（Y-Bocs）. Results：Patients with obsessive-compulsive disorder exhibited poorer performance in BMT（respectively,5.6±2.5 vs 9.2±4.1） than those in panic patients（7.6±4.2 vs 12.1±4.3） and those in controls（7.6±3.4 vs 11.6±5.0） when interval of masking was 30 milliseconds and 50 milliseconds while there was no significant difference in BMT among the three groups without interfere stimulus.As to CPT,there was no significant difference among three groups（P0.05）.No direct relationship between scores on MOCI,Y-BOCS and correct response in BMT was observed. Conclusion：Patients with obsessive-compulsive disorder may have decreased selective attention,while panic patients may have no attention impairments.

关 键 词：强迫障碍 惊恐障碍 倒行掩蔽测验 连续操作测验 

分 类 号：R749[医药卫生—神经病学与精神病学]