定标活检评价氩离子凝固术治疗Barrett食管的随访分析  

Application of marking targeting biopsy in evaluation of argon plasma coagulation in treatment of Barrett's esophagus

作　　者：吴益群 林琪 劳波 洪捷敏 尹雪 张佩翡 

机构地区：[1]宁波市鄞州区第二医院消化内科,315100

出　　处：《浙江医学》2013年第6期447-449,共3页Zhejiang Medical Journal

基　　金：浙江省医药卫生科技计划项目资助(2010KYB099)

摘　　要：目的通过定标活检术评价氩离子凝固术(APC)对Barrett食管(BE)疗效。方法选择2010年3月至2011年3月经胃镜和定标活检后病理证实的BE患者35例,予以行APC,术后辅以质子泵抑制剂治疗,通过定标处内镜下所见及病理结果评价其疗效,并分析并发症等情况。结果 35例患者共行40次APC治疗,平均1.14次/例,经治疗后34例(97.1%)获得BE完全逆转。单次定标成功率100%,随访超过6、10及12个月的患者中,定标存在率分别为100%、93.3%及77.8%。结论 APC治疗BE安全有效,用定标活检术评价APC治疗BE更为科学和精确。Objective To evaluate the efficacy of argon plasma coagulation（APC） in treatment of Barrett＇s esophagus with marking targeting biopsy. Methods Thirty five patients with Barrett＇s esophagus underwent APC and received acid suppression treatment from March 2010 to March 2011. The efficacy and complications were followed up with marking targeting biopsy. Results The complete squamous regeneration was achieved in 34 patients （97.1%） after total 40 APC sessions with a mean of 1.14/patient. Single marking targeting biopsy was successfully carried out in all patients. The rates of mark existence were 100%, 93.3% and 77.8% during follow up for 6, 10 and 12 months, respectively. Conclusion The marking targeting biopsy provides an effective and accurate method for evaluation of the efficacy of argon plasma coagulation in treatment of Barrett＇s esophagus.

关 键 词：定标活检 BARRETT食管 氩离子凝固术 

分 类 号：R571[医药卫生—消化系统]