卡培他滨联合奥沙利铂治疗老年晚期胃癌的临床观察  

Capecitabine combined treatment of senile oxaliplatin into advanced gastric cancer clinical observation

作　　者：苏奕欣[1] 

机构地区：[1]广西灵山县人民医院肿瘤科,535400

出　　处：《中国实用医药》2013年第7期24-25,共2页China Practical Medicine

摘　　要：目的探讨应用卡培他滨联合奥沙利铂在老年晚期胃癌治疗效果。方法将66例老年晚期胃癌患者随机分为治疗组及对照组,治疗组33例应用奥沙利铂联合卡培他滨治疗,对照组ELF方案化疗。结果化疗6周后(2个周期)观察疗效,治疗组有效率93.9%,与对照组有效率78.8%比较,对照组的3～4级恶心呕吐21例,骨髓抑制11例,治疗组恶心呕吐10例,骨髓抑制3例。差异有统计学意义(P<0.05)。结论卡培他滨联合奥沙利铂治疗老年晚期胃癌疗效肯定,毒性反应轻微,患者易于接受,依从性高,生活质量明显提高,值得基层医院进一步推广应用。Objective To evaluate the effect of capecitabine joint oxaliplatin into old age in advanced gastric cancer treatment effect. Methods 66 elderly cases of advanced gastric cancer patients were randomly divided into treatment group and control group, treatment group 33 cases of application of oxaliplatin into joint capecitabine treatment group, ELF scheme chemotherapy. Results 6 weeks after chemotherapy （two cycle）to observe curative effect, the effective rate was 93.9% in treatment group and 78.8% in control group efficient comparison, control group 3~4 level 21 cases of nausea and vomiting, bone marrow suppression 11 cases, the treatment group nausea and vomiting 10 cases, 3 cases of bone marrow suppression. Difference have statistical significance （P0.05）. Conclusion Capecitabine combined treatment of senile oxaliplatin into advanced gastric cancer curative effect affirmation, toxicity was mild, patients easy to accept, compliance is high, the quality of life is obviously improved and the basic-level hospitals is worth further popularization and application.

关 键 词：老年晚期胃癌 奥沙利铂 卡培他滨 化疗 

分 类 号：R735.2[医药卫生—肿瘤]