106例青年乳腺癌患者的临床病理分析  

Clinical pathological features in 106 cases of young breast cancer

作　　者：黄冬凌[1,2] 叶长生[3] 姚广裕[3] 

机构地区：[1]南方医科大学,广州510515 [2]深圳市宝安区人民医院 [3]南方医科大学附属南方医院乳腺科

出　　处：《新医学》2013年第3期162-165,共4页Journal of New Medicine

摘　　要：目的:探讨青年乳腺癌的临床病理特点。方法:比较106例青年乳腺癌(≤35岁)患者和640例中老年乳腺癌患者的临床病理类型、雌激素受体(ER)和孕激素受体(PR)、Her-2蛋白、Ki-67及P53表达和淋巴结转移情况。结果:青年组和中老年组在病理类型方面均以浸润性导管癌为主,比较差异无统计学意义(P>0.05);青年组与中老年组在各组织学等级所占比例比较差异无统计学意义(P>0.05);青年组ER、PR阳性表达率低于中老年组,而Her-2及Ki-67阳性表达率高于中老年组(均为P<0.05)。结论:青年乳腺癌具有侵袭性强,易发生转移等特点。Objective ： To study the pathological characteristics of young breast cancer. Method： The patho- logical type, expression percentage of ER, PR, Her-2 gene and lymphatic metastases of 106 cases of young breast cancer （ less than 35 years） and 640 cases of middle aged and aged breast cancer were analyzed. Result： The in- filtrating ductal carcinoma is the principle pathological type in both series of breast carcinoma （P 〉 0.05 ）. About the histological grading there were no difference between the two series of breast carcinoma （ P 〉 0.05 ） ; The rate of expression of hormone receptors （ ER, PR, Ki-67 and Her-2 gene） of the two series of breast carcinoma had statistical significance difference （ P 〈 0 05 ）. Conclusion： Young breast cancer had the feature of strong invasion and high rate of lymphatic metastase.

关 键 词：青年女性 乳腺癌 病理特点 

分 类 号：R737.9[医药卫生—肿瘤]