Landau-Kleffner综合征一例  

A case of Landau-Kleffner syndrome

作　　者：周妍[1] 李建英[1] 邓红珠[1] 邹小兵[1] 

机构地区：[1]中山大学附属第三医院儿科,广州510630

出　　处：《新医学》2013年第3期211-213,共3页Journal of New Medicine

摘　　要：Landau-Kleffner综合征(LKS)是一种儿童的少见疾病,临床症状以获得性失语、癫痫发作表现为主,异常脑电图及排除脑结构性异常是诊断关键,免疫球蛋白与拉莫三嗪、糖皮质激素3者联合治疗是主要的治疗方法之一。该文总结分析1例LKS的诊治经过,并进行文献复习。该例患者有获得性失语、癫痫发作病史,结合患儿脑电图、实验室及影像学检查最终诊断为LKS。经联合治疗收效良好,患儿癫痫未再发作,语言完全恢复,复查常规脑电图示正常。Landau-Kleffner syndrome （LKS） is an rare disease in children. To explore the main points of di- agnosis and treatment in LKS, we analysed and summarize the diagnosis and treatment procedures of one patient with LKS. The patient with acquired aphasia and the history of epileptic seizure, combining with the electroenceph- alogram （EEG） findings, laboratory examination and imaging examination can diagnosis for LKS. The symptoms have improved with the combined treatment, no epilepsy attack, language capability recovery, reexamine the EEG findings were normal. The main clinical symptoms of LKS were acquired aphasia and epileptic seizure. The exclu- sion of abnormal EEG and brain structure were the diagnostic keys. The combined treatment with IVIG, lamotrigine and glucocorticoid is one of the main treatment methods.

关 键 词：Landau—Kleffner综合征 获得性失语 癫痫发作 

分 类 号：R742.1[医药卫生—神经病学与精神病学]