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机构地区:[1]上海市儿童医院上海交通大学附属儿章医院儿童保健所,200040
出 处:《中华实用儿科临床杂志》2013年第5期370-372,共3页Chinese Journal of Applied Clinical Pediatrics
基 金:国家自然科学基金(30801205);上海市科委青年科技启明星资助项目(09QA1404800);上海市科委自然科学基金(12ZR1425600)
摘 要:目的探讨注意缺陷多动障碍(ADHD)与肥胖的分布特点。方法采用《精神障碍诊断和统计手册》第4版(DSM-Ⅳ)诊断标准确诊的ADHD患儿239例为ADHD组,常规体检儿童137例为健康对照组,2组均进行体格测量,根据WHO的儿童肥胖标准,评价正常、超重及肥胖,比较ADHD组与健康对照组及ADHD组各亚型间超重及肥胖率有无差异。结果ADHD组超重+肥胖率[98例(41.0%)]与健康对照组[39例(28.5%)]比较差异有统计学意义(P〈0.01);ADHD组超重率[41例(17.2%)]与健康对照组[22例(16.1%)]比较差异无统计学意义;ADHD组肥胖率[57例(23.8%)]与健康对照组比较[17例(12.4%)]差异有统计学意义(P〈0.01);ADHD各亚型中,Ⅰ型(注意力缺陷型)超重+肥胖率与健康对照组比较差异有统计学意义(超重16例,肥胖19例,占40.3%);Ⅱ型(多动冲动型)超重+肥胖率与健康对照组比较差异无统计学意义(超重5例,肥胖8例,占36.1%);Ⅲ型(混合型)超重+肥胖率与健康对照组比较差异有统计学意义(超重20例,肥胖30例,占40.3%);3个亚型组间超重、肥胖率比较差异均无统计学意义(P均〉0.05);以超重、肥胖与否分组,超重+肥胖组ADHD发病率显著高于体质量正常组(P〈0.05)。结论肥胖症为ADHD的高危因素,二者内在发病机制可能有交叉。Objective To investigate the distribution characteristics between attention-deficit hyperactivity disorder(ADHD) and obesity. Methods Two hundred and thirty-nine children diagnosed as ADHD meeting the ADHD criteria of DSM-1V and 137 healthy children were enrolled in ADHD group and healthy control group, respectively. An- thropometric measurement and nutritional assessment were performed for the 2 groups. The incidences of overweight and obesity among each group were compared. Results There was significant difference in the incidence of overweight + obesity between ADHD group and healthy control group 198 cases (41.0%) vs 39 cases ( 28.5% ) ] ; No significant difference in the incidence of overweight was observed between ADHD group and healthy control group E 41 cases ( 17.2% ) vs 22 cases( 16.1% ), P 〉 0.05 J. The incidence of ADHD in overweight + obesity group was significantly higher than that in healthy control group. The incidence of obesity in ADHD group was significantly higher than that in healthy control group E 57 cases (23.8%) vs 17 cases ( 12.4% ) , P 〈 0.01 ]. The incidence of overweight + obesity in the subtype I and subtype III was significantly higher than healthy control group ;There was no significant difference in the incidence of overweight + obesity between the subtype II group and healthy control group. There was no significant difference in the incidence of overweight + obesity among each subtype group of the ADHD ( P 〉 0.05 ). The incidence of ADHD in the overweight + obesity group was significanthy than that in normal weight group( P 〈0.05 ). Conclusion Obesity is a risk factor of ADHD, and their pathogenesis may be over/apping.
分 类 号:R749.94[医药卫生—神经病学与精神病学]
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