年龄相关白内障患者角膜生物测量参数的分布及相互关系的研究  

Analysis of corneal biometric parameters of age - related cataract patients

作　　者：马冬梅[1] 张健[1] 方薇[1] 蒋慧中[1] 杨惠青[1] 刘大川[1] 

机构地区：[1]首都医科大学宣武医院眼科,北京100053

出　　处：《中华眼外伤职业眼病杂志》2013年第4期254-258,共5页Chinese Journal of Ocular Trauma and Occupational Eye Disease

基　　金：北京市委组织部优秀人才资助项目（20051D0501821）首都医科大学基础临床科研合作基金重点课题资助项目（1000172404）

摘　　要：目的研究年龄相关白内障患者角膜生物测量参数分布规律及其相互关系。方法采用光学相干生物测量仪（IOL Master）对1003名（1526眼）白内障患者进行角膜生物测量，应用SPSS13．0统计软件对数据进行统计分析。结果患者年龄中位数为74岁，平均角膜曲率（44．59±1．68）D，年龄与角膜曲率呈负相关关系（r=-0．073，P=0．000）。角膜散光中位数为0．95D，角膜散光〈1．0D的占54．5％，1．0．2．0D的占34．O％，角膜散光〉2．0D的占11．5％，年龄与角膜散光呈正相关关系（r=0．143，P=0．000）。随着年龄增长，顺规散光比例由64．6％减少为22．2％，逆规散光比例由18．8％增至66．7％。结论年龄相关性白内障患者角膜散光的患病率较高，且以1．0D以内的轻度散光为主。随着年龄增长，角膜曲率有减小的趋势，角膜散光有增大的趋势，散光类型从顺规散光向逆规散光漂移。Objective To analyze the distribution and correlation of corneal biometric parameters in patients with Aye - related cataract. Methods 1526 eyes of 1003 patients aged 40 years and older were recruited for this study. The corneal curvature and astigmatism were optically measured by partial coherence interferometry （IOLMaster）. Statistical software package SPSS 13.0 was used to analyze statistically. Resuits The median age of the patients was 74 years （ range 40 to 95 years）. The mean of corneal curvature was （44.59 ＋ 1.68 ） diopter （ D）, normal distribution. There was negative relationship between age and corneal curvature （ r = - 0. 073, P = 0. 000）. The median corneal astigmatism was 0.95D, non - normal distribution. It was 1.0D or less in 831 eyes （54.4%）, 1.0D - 2.0D in 519 eyes （34.0%）, and more than 2.0D in 176 eyes（ 11.4% ）. There was positive relationship between age and corneal astigmatism （r = 0. 143, P = O. 000 ）. With aging, the percent of with - the - rule （ WTR ） astigmatism decreased from 64.6% to 22.2%, and against - the - rule （ATR） astigmatism increased from 18.8% to 66.7%. Conclusion Corneal astigmatism less than 1.0D was present in most patients with cataract. Corneal curvature ten- ded to decrease with aging while corneal astigmatism tended to increase. The pattern of corneal astigmatism shifted from WTR to ATR astigmatism.

关 键 词：白内障 生物测量 角膜 散光 角膜曲率 

分 类 号：R776.1[医药卫生—眼科]