高龄老年人睡眠质量与认知功能的相关性分析  

Relationship between sleep quality and cognitive impairment in elderly veterans

作　　者：张宝和[1] 王吉[1] 孙洪良[1] 吴慧[1] 陈春雷[1] 王巍[1] 尚毅[1] 张洋[1] 华伟[1] 李鲁[1] 胡晓东[1] 胡婷婷[1] 叶光华 宋水 李鑫 李朝印 张荣强 张凤斋 谭纪萍[8] 王鲁宁[8] 

机构地区：[1]海军总医院干部保健科,北京100048 [2]海军香山干休所门诊部,北京100093 [3]海军万寿路干休所门诊部,北京100036 [4]海军复兴路干休所门诊部,北京100841 [5]海军阜成路干休所门诊部,北京100036 [6]海军丰台干休所门诊部,北京100071 [7]海军小井干休所门诊部,北京100073 [8]解放军总医院南楼神经内科,北京100853

出　　处：《转化医学杂志》2013年第2期99-102,共4页Translational Medicine Journal

基　　金：全军保健专项项目(07BJZ04)

摘　　要：目的检查高龄离退休老年人睡眠质量及认知功能,并分析两者相关性。方法利用蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)、简易智能状态量表(mini-mental state examination,MMSE)、匹兹堡睡眠质量指数量表(Pittsburgh sleep quality index,PSQI),检查325例高龄离退休老年人睡眠质量及认知功能,分析评估其相关关系。结果 325例PSQI平均得分为(5.66±4.27)分,睡眠障碍102例,发生率为31.38%。认知损害95例,发生率29.23%;其中,轻度认知障碍(mild cognitive impairment,MCI)82例,患病率25.23%;阿尔茨海默病13例,患病率4.00%。睡眠障碍组认知损害患病率增加(χ2=12.544,P=0.002)。睡眠质量指数得分与蒙特利尔认知评估量表得分呈负相关(r=-0.194,P<0.05)。部分PSQI子项目与视空间、注意力、语言、延迟回忆、定向力等认知功能呈负相关关系(P<0.05)。结论高龄离退休老年人睡眠质量较差,睡眠质量与认知损害存在相关性。Objective To explore the relationship between sleep quality and cognitive impairment in elderly veterans. Methods Three hundred twenty five veterans aged over 60 years from 6 military sanatorium in Beijing city were evaluated with Pittsburgh sleep quality index （PSQI）, Minimental state examination （MMSE） and Montreal cognitive assessment （MoCA）from January 2010 to December 2011. Results The mean score of PSQI was （ 5.66±4. 27 ） , and the amount of sleep disorders was 102, the prevalence was 31.38%. The amount of veterans with cognitive impairment was 95, the prevalence was 29.23%, the amount of veterans with Mild Cognitive Impairment and Alzheimer＇s disease were 82 and 13 respectively. The occurrence of cognitive impairment was higher in sleep disorders patients than that in control. The correlation analysis was negative between some items of PSQI and MoCA. Conclusion The incidence of sleep disorder in elderly veterans was high, and there was correlation between sleep quality and cognitive impairment.

关 键 词：睡眠障碍 认知损害 相关性 老年人 

分 类 号：R741[医药卫生—神经病学与精神病学]