睡眠质量与青年脑梗死相关性的研究  

Correlation of Sleep Quality with Cerebral Infarction in Young

作　　者：赵晶[1,2,3] 钱进军[2,3] 巩企霞[1] 

机构地区：[1]江苏大学临床医学院 [2]江苏大学第四附属医院 [3]镇江市第四人民医院神经内科,江苏镇江212001

出　　处：《中国医药指南》2013年第4期48-50,共3页Guide of China Medicine

摘　　要：目的探讨青年脑梗死的危险因素及睡眠质量对青年脑梗死发病的影响。方法选取青年脑梗死患者81例及同期体检正常的青年75例,（年龄均为18～45岁）。比较两组的一般临床资料,分析青年脑梗死的危险因素。采用匹兹堡睡眠质量指数（PSQI）量表进行睡眠质量评价。观察睡眠质量与青年脑梗死发病的关系。结果青年脑梗死组PSQI总分（8.49±4.42）明显高于对照组（5.75±3.96）,（P〈0.05）;PSQI总分≥7分,存在睡眠质量问题,其中青年脑梗死组48例（59.26%）、对照组24例（32%）,两组比较差异有统计学意义（P〈0.05）;PSQI各因子中,睡眠质量,睡眠效率,睡眠障碍,催眠药物,日间功能障碍评分两组间均有显著性差异（P〈0.05）;多变量Logistic回归分析得出高血压,高同型半胱氨酸血症,吸烟,日间功能障碍是青年脑梗死的危险因素（OR〉1）;睡眠时间6~7h是青年脑梗死的保护因素（OR〈1）。结论睡眠质量与青年脑梗死密切相关,日间功能障碍是青年脑梗死的一个危险因素,睡眠时间6~7h是青年脑梗死的一个保护因素。高血压,高同型半胱氨酸血症,吸烟也是青年脑梗死的危险因素。Objective To explore risk factors of youth cerebral infarction and to investigate the correlation of sleep quality with cerebral infarction in young. Methods 81 young adults with cerebral infarction and 75 healthy young subjects were selected （the range of age was 18-45 years）.Compare the clinical data between the two groups, and analyze risk factors of youth cerebral infarction. Sleep quality assessment was performed by using Pittsburgh Sleep Quality Index （PSQI）. The correlation of sleep quality with cerebral infarction was explored. Results The PSQI scores in patients （8.49±4.42）was significantly higher as compared with that in controls （5.75±3.96）, （P〈0.05）;There were about 59.26% persons whose PSQI scores exceed 7 had a bad sleep in patients ,about 32% persons whose PSQI scores exceed 7 had a bad sleep in controls. The difference between two groups was significantly （P〈0.05）; The scores of sleep quality, sleep efficiency, sleep disorders, Hypnotic drugs and daytime dysfunction among two groups were significantly different （P〈0.05）. With multivariate Logistic regression analysis, high blood pressure, hyperhomocystinemia, smoking, daytime dysfunction are risk factors of youth cerebral infarction （OR〉l）; Sleep time 6 - 7 hours prevent from youth cerebral infarction （OR〈1）. Conclusion A close correlation between cerebral infarction in young and the PSQI scores exists, with sleep time 6 - 7 hours being a protective factor and daytime dysfunction being a risk factor for clinical cerebral infarction in young adults.And high blood pressure, hyperhomoeystinemia, smoking, are also risk factors of youth cerebral infarction.

关 键 词：脑梗死 青年 睡眠质量 PSQI量表 

分 类 号：R743.3[医药卫生—神经病学与精神病学]