脑梗死后认知损害与神经功能恢复关系的研究  被引量:15

The Correlation between Cognitive Impairment after Cerebral Infarction and the Recovery of Neurological Function of Patients with Cerebral Infarction

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作  者:何奕涛[1] 邹良玉[1] 付学军[1] 唐冰杉[1] 张莹[1] 马可夫[1] 郭毅[1] 

机构地区:[1]暨南大学第二临床医学院(深圳市人民医院)神经内科,广东深圳518020

出  处:《神经损伤与功能重建》2013年第2期124-126,共3页Neural Injury and Functional Reconstruction

基  金:广东省科技厅项目(No.2011B031800130);深圳市卫生局重点项目(No.201101020)

摘  要:目的:评价脑梗死后认知功能损害与神经功能恢复的相关性。方法:连续纳入脑梗死患者211例,根据蒙特利尔认知评估量表(MoCA)测评结果分为无认知损害组46例及认知损害组165例,比较2组患者入选时和随访3个月时的Barthel指数(BI)及美国国立卫生院脑卒中量表(NIHSS)评分及其改善程度;并评估MoCA分值与BI和NIHSS评分及其改善程度的相关性。结果:在入选时及随访3个月时,无认知损害组患者NIHSS评分低于且BI评分高于认知损害组患者(P<0.05),BI及NIHSS评分的改善程度均大于认知损害组(P<0.05);入选时及随访3个月时,所有患者MoCA分值与NIHSS评分呈负相关,与BI评分呈正相关,与BI及NIHSS评分的改善程度呈正相关(P<0.05)。结论:脑梗死后的认知功能损害会阻碍患者神经功能的恢复。Objective: To assess the association between cognitive impairment and the recovery of neuro- logical function in patients with cerebral infarction. Methods: Two hundred and eleven cases of acute cerebral infarction were enrolled and divided into no cognitive impairment group and cognitive impairment group based on Mont-real Cognitive Assessment (MoCA). Barthel Index (BI) and National Institutes of Health Stroke Scale (NIHSS) score for all participants at enrollment and 3 months after strokes were documented and analyzed. Re- suits: At enrollment and month 3, in the no-cognitive impairment group the NIHSS scores was lower and the BI scores higher than those in the cognitive impairment group (P〈0.05). The MoCA scores was negatively cor- related with NIHSS scores and positively correlated with BI scores (P〈0.05). Conclusion: Cognitive impairment after cerebral infarction will obstruct the recovery of neurological function.

关 键 词:脑梗死 认知功能损害 神经功能恢复 

分 类 号:R741[医药卫生—神经病学与精神病学] R743[医药卫生—临床医学]

 

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