乳腺纤维腺瘤超声造影特征表现及诊断  

Contrast-enhanced Ultrasonography in Character and Diagnosis of Breast Fibroadenoma

作　　者：王小燕[1] 蓝春勇[1] 韦海明[2] 黄向红[1] 农美芬[1] 贺琰[1] 裴华洁[1] 

机构地区：[1]广西壮族自治区人民医院超声科,南宁市530021 [2]广西壮族自治区人民医院病理科,南宁市530021

出　　处：《中国超声医学杂志》2013年第4期316-320,共5页Chinese Journal of Ultrasound in Medicine

基　　金：广西科学研究与技术开发计划项目(No.桂科攻0592007-2c)

摘　　要：目的探讨实时超声造影检查对乳腺纤维腺瘤病灶的诊断及鉴别价值。方法选用SonoVue超声造影剂,对经手术及病理证实的47例乳腺纤维腺瘤患者进行彩色多普勒超声造影,对肿块的增强形态、强度及造影时间-强度曲线特征进行分型,并将其超声造影的特征与病理组织学特征进行对照分析。结果纤维腺瘤组47例造影强度分别为高增强12例,等增强12例,低增强16例,极少至无增强7例,照影剂进入肿块的大小及范围常与二维超声图像一致,且边界常呈环状增强或半环状增强;内部可呈均匀及不均匀增强,当纤维腺瘤伴广泛玻璃变及钙盐沉积时,内常无造影剂进入;该组时间-强度曲线常呈"慢上快下及快上快下"型;超声造影诊断良性肿瘤的符合率为89.4%(42/47)。结论乳腺纤维腺瘤病灶在超声造影下可具有一定的造影特征,超声造影有助于提高乳腺肿瘤的诊断准确率。Objective To observe the value of real-time contrast-enhanced ultrasonography in character and diag nosis of breast fibroadenoma. Methods Totally 47 patients of breast fibroadenoma were observed by Color Doppler real-time contrast enhanced ultrasonography using SonoVue. The enhancement form, intensity and time-intensity curve were classified respectively, and characteristics of contrast-enhanced and pathological were analyzed. Results The contrast-enhanced intensity of 47 patients of breast fibroadenoma, 12 cases were high enhancement, 12 were equal enhancement, 16 were low enhancement and 7 were no enhancement, The size and scope of contrast agent into the lump＂ were similar to those of the two-dimensional ultrasound image, linear ring and half-ring enhancement were very common in lump＇s boundary. Inhomogeneous partial enhancement and entire enhancement appeared in most of lump＇s inside. The breast fibroadenoma with a wide range of glass transition and calcium deposition, often appeared without the contrast agent in the inner. The time-intensity curve of the benign group displayed ＂slow washin and fast washout＂ and ＂ fast washin and washout＂ The accuracy of contrast-enhanced ultrasonography were 89.4G （42/47）. Conclusions The enhancement modes have different characters in breast fibroadenoma. Real time contrast-enhanced ultrasound helps to improve the diagnostic accuracy of breast fibroadenoma.

关 键 词：实时超声造影 乳腺纤维腺瘤 超声造影诊断 彩色多普勒超声造影 SONOVUE 病理组织学特征 超声造影剂 二维超声图像 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]