老年抑郁症者5-羟色胺再摄取抑制剂撤药反应(附3例报告)  

Pay more attention to withdrawal symptoms of selective serotonin reuptake inhibitors in elderly depressed patients (Three Cases Reports)

作　　者：郑辉[1] 陈晓燕[1] 刘谦[1] 秦明照[1] 

机构地区：[1]首都医科大学附属北京同仁医院内科,100730

出　　处：《北京医学》2013年第4期267-269,共3页Beijing Medical Journal

摘　　要：目的探讨老年患者5-羟色胺(5-HT)再摄取抑制剂(SSRIs)撤药反应。方法结合文献对3例老年抑郁症患者SSRIs撤药反应进行分析。结果 3例老年患者均出现不同程度的与SSRIs撤药相关的精神及躯体症状,其中以停用帕罗西汀患者症状较为明显。结论老年抑郁症患者SSRIs撤药反应发生率较高,影响较大,应引起非精神科医生高度重视。Objective To emphasis on unawareness of withdrawal symptoms of selective serotonin reuptake inhibitors （SSRIs） in elderly depressed patients by reporting 3 cases. Methods Withdrawal symptoms of SSRIs in three elderly depressed patients were analyzed and the relevant literature were reviewed. Results Three cases of elderly patients with varying degrees of mental and physical symptoms related to withdrawal of SSRIs were described. The withdrawal symptoms of paroxetine in patients were more evidentthan other SSRIs. Conclusion Elderly patients with depression have a higher incidence of withdrawal phenomenon of SSRIs. The withdrawal phenomenon has great impact on elder patients. Physicians who prescribe SSRIs should be aware of this special condition in elder depressed patients.

关 键 词：老年患者 5-羟色胺再摄取抑制剂 撤药反应 

分 类 号：R749.4[医药卫生—神经病学与精神病学]