放射性脑坏死的MRI诊断  

MRI DIAGNOSIS OF BRAIN RADIATION NECROSIS

作　　者：吴慧[1] 牛广明[1] 韩晓东[1] 高阳[1] 张颖[1] 

机构地区：[1]内蒙古医科大学附属医院磁共振室,内蒙古呼和浩特010050

出　　处：《内蒙古医科大学学报》2013年第1期21-26,共6页Journal of Inner Mongolia Medical University

基　　金：内蒙古自然科学基金(2012ms1184)

摘　　要：目的:探讨放射性脑坏死(Brain radiation necrosis,BRN)的MRI诊断和鉴别诊断。方法:回顾性分析本院10例BRN病人资料,所有病例均行MRI平扫、增强扫描、灌注成像(PWI)。结果:这10例病例中8例具有MRI的特异性表现:T1WI呈低信号,T2WI呈高信号,信号不均匀,病灶呈不均匀明显强化,强化灶外形不规则呈粗大齿轮状,水肿沿白质蔓延呈爪状。磁共振灌注成像(PWI):8例呈低灌注,2例呈无灌注;10例脑血容量(rCBV)均减低。结论:BRN与肿瘤复发在影像表现与临床上很相似,往往不易区分,容易误诊,应综合病人病史、发病时间、MRI平扫、增强扫描的特异性表现,同时结合PWI不难鉴别。Objective： To investigate the MRI diagnosis and differential diagnosis of BRN. Methods：The data of 10 BRN cases was reviewed. All cases had plain MRI scan and contrast enhancement scan, PWI. Results： 8 cases had MRI specific performance： long T1 and long T2 with signal heterogeneous, lesions showed heterogeneous marked enhancement, strengthen shapes were bulky gear like, the edemas spread along the white matter showed a claw- like. PWI： 8 cases were hypoperfused ,2 cases were nonperfused. 10 cases rCBV were all reduced. Conclusions：It is difficult to differentiate BRN from glioma recurrence. The medical history, the morbidity time, the special appearance of MRI, PWI may contribute to diagnose.

关 键 词：放射性脑坏死 放射治疗 灌注成像 

分 类 号：R445.4[医药卫生—影像医学与核医学]